2-aryl selenazole compound and pharmaceutical composition thereof

A compound represented by formula (I) or a pharmaceutically acceptable salt thereof,

• wherein,
• X is selected from C1-2 alkyl or substituted C1-2 alkyl;
• Y is selected from —COORa or —CONHRa;
• R1 is selected from halogen, —CN, C1-2 alkyl, substituted C1-2 alkyl, C1-3 alkoxy, or substituted C1-3 alkoxy;
• R2 is selected from H, D, halogen, C1-2 alkyl, substituted C1-2 alkyl, C1-3 alkoxy, or substituted C1-3 alkoxy;
• and
• R3 is selected from —(CH2)n—O—Rb, —(CH2)n—S—Rb, —C(O)Rb, —NRcRd, —S(O)CHRcRd, —S(O)2CHRcRd, —(CH2)nC(O)NRcRd, aryl, substituted aryl, a heterocyclic radical, a substituted heterocyclic radical, a heteroaryl radical, or a substituted heteroaryl radical, wherein,
• n is 0 to 2;
• Ra is selected from H, C1-6 alkyl or substituted C1-6 alkyl;
• Rb is selected from H, methyl, ethyl, propyl, 2-propyl, butyl, tertiary butyl, amyl, substituted C1-8 alkyl, aryl, substituted aryl, a heterocyclic radical, a substituted heterocyclic radical, a heteroaryl radical, or a substituted heteroaryl radical;
• and
• Rc and Rd are respectively independently selected from H, C1-8 alkyl, or substituted C1-8 alkyl;
• or Rc and Rd are cyclized to form cycloalkyl, substituted cycloalkyl, a heteroaryl radical, or a substituted heteroaryl radical;
• and
• a substituent in groups X, Y, R1, R2, R3, Ra, Rb, Rc or Rd is selected from one or more of D, —OH, —CN, —NH2, acyl, acylamino, halogen, C1-4 alkyl, halogenated C1-4 alkyl, deuterated C1-4 alkyl, C1-2alkoxy, or C1-2 alkylamino.