Liner-based liquid storage and dispensing systems with empty detection capability

A fluid storage and dispensing system, comprising:

• a vessel having an interior volume;
• a liner in said interior volume, said liner arranged to contain a liquid medium;
• a dispensing assembly adapted to engage the vessel and to withdraw liquid medium from the liner during dispensing operation;
• at least one pressure sensor arranged to monitor at least one condition indicative of withdrawal of said liquid medium from the liner during dispensing operation,
• a dispense line operatively coupled to the dispensing assembly to dispense said liquid medium at a dispense line pressure;
• and
• a drive train adapted to generate drive train pressure for applying pressure to the liner for pressure dispensing of the liquid medium from the liner;
• wherein the at least one pressure sensor is arranged to generate an output in response to a change in said dispense line pressure indicative of the onset of exhaustion of liquid medium from the liner wherein at least some liquid remains in the liner, and said drive train is adapted to increase said drive train pressure responsive to said output so as to maintain a desired dispense line pressure.