Flowable matrix compositions and methods
AssigneeAlloSource
InventorsReginald L. Stilwell, Adrian C. Samaniego, Brent Atkinson
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Abstract
Flowable matrix compositions and methods of their use and manufacture are provided. Exemplary compositions may include a flowable, syringeable, putty-like form of acellular human dermal matrix. In some cases, compositions may include a moldable acellular collagen extracellular matrix. In use, the matrix compositions can be used to fill or treat skin voids, channel wounds, and other soft tissue deficiencies.
Claims39
A method for producing a soft tissue matrix composition for use in a patient treatment, the method comprising:
- providing a human soft tissue material, wherein the human soft tissue material is in a partially hydrated state;
- and
- processing the human soft tissue material by cryofracturing the human soft tissue material,
- wherein the processing provides the soft tissue matrix composition, the soft tissue matrix composition comprising a substantial amount of the natural interstitial water of the human soft tissue material that is present prior to cryofractionation.
A method for producing a soft tissue matrix composition for use in a patient treatment, the method comprising:
- providing a human soft tissue material, wherein the human soft tissue material is in a naturally hydrated state;
- and
- processing the human soft tissue material by cryofracturing the human soft tissue material,
- wherein the processing provides the soft tissue matrix composition, the soft tissue matrix composition comprising the natural interstitial water of the human soft tissue material that is present prior to cryofractionation.
Dependencies are inferred from the claim text.