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US 9,801,952 B2Granted
Magnetic nanostructures as theranostic agents
AssigneeNorthwestern University
InventorVinayak P. Dravid
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Abstract
The present invention relates to magnetic nanostructures as theranostic agents, which provide dual function as diagnostic and therapeutic agents. In particular, the present invention relates to compositions comprising magnetic nanostructures and their use as targeted therapeutic agents for cancers (e.g., medulloblastoma) and Alzheimer's disease and related diseases and conditions.
Claims9
A method, comprising
- a) administering a magnetic nanostructure comprising i) a magnetic nanostructure coated with a non-magnetic coating;
- and ii) a targeting agent, wherein said targeting agent targets said nanostructure to a Medulloblastoma cell of a subject;
- b) detecting the presence of said cancer cell in said subject by identifying said magnetic nanostructure;
- and
- c) destroying said cancer cell by exposing said magnetic nanostructure to a radio frequency that causes said magnetic nanostructure to generate heat.
2 more elements
A method, comprising
- a) administering a magnetic nanostructure comprising i) a magnetic nanostructure coated with a non-magnetic coating;
- and ii) a targeting agent, wherein said targeting agent targets said nanostructure to a Medulloblastoma cell to a subject;
- and
- b) detecting the presence of said cancer cell in said subject by identifying said magnetic nanostructure.
1 more element
Dependencies are inferred from the claim text.