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US 9,801,949 B2Granted
Combinations of albumin-based drug delivery systems
AssigneeKtb Tumorforschungsgesellschaft Mbh
InventorsFelix Kratz, Andre Warnecke
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Abstract
The present invention relates to a composition comprising at least two different albumin-based drug delivery systems, as well as to a pharmaceutical composition comprising said composition.
Claims3
A composition comprising a combination of at least two different albumin-binding prodrugs, wherein one of said at least two different albumin-binding prodrugs is the 6-maleimidocaproyl(hydrazone) derivative of doxorubicin (DOXO-EMCH), and wherein one of the at least two different albumin-binding prodrugs is the methotrexate derivative EMC-D-Ala-Phe-Lys-Lys(γ-MTX)-OH, wherein EMC=6-maleimidocaproic acid, (AW054).
Dependencies are inferred from the claim text.