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US 9,801,939 B2Granted
Compositions and methods for reducing overdose
AssigneeIsa Odidi
InventorIsa Odidi
Life of this patent
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Abstract
Drug delivery formulations, uses thereof and methods of making same are provided in order to reduce the potential for abuse, misuse or improper administration of an addictive substance or any active substance and to prevent, reduce, inhibit, or delay purposeful or accidental overdose of an active substance by ingesting too many dosage forms at once, for example.
Claims48
A unit dose formulation comprising:
- at least one active substance, wherein release of said at least one active substance is inhibited when the number of unit dosage forms ingested exceeds a predetermined number;
- at least one actuator partially, substantially, or completely surrounding at least one active substance;
- and
- at least one regulator,
- whereby when the unit dose formulation is exposed to a fluid media having a process variable, said process variable being pH, said at least one regulator is capable of adjusting the pH to inhibit the release of said at least one active substance via said at least one actuator, when the number of unit dosage forms exceeds the predetermined number.
2 more elements
Dependencies are inferred from the claim text.