Parenteral norovirus vaccine formulations
AssigneeTakeda Vaccines, Inc.
InventorsCharles Richardson, Thomas R. Foubert
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Abstract
The present invention relates to single dose parenteral vaccine compositions comprising mixtures of monovalent Norovirus virus-like particles. Methods of conferring protective immunity against Norovirus infections in a human subject by administering such compositions are also disclosed.
Claims18
A buffered composition comprising a first monovalent VLP derived from a first Norovirus genogroup and a second monovalent VLP derived from a second Norovirus genogroup, wherein the first Norovirus genogroup is genogroup I and the second Norovirus genogroup is genogroup II, wherein said buffer is selected from L-histidine and imidazole, and wherein the composition is formulated as a liquid.
Dependencies are inferred from the claim text.