Use of pertussis toxin as a therapeutic agent
AssigneeDignity Health
InventorJiong Shi
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Abstract
The present application relates to the use of a pertussis toxin, and its derivatives, analogs, salts and pharmaceutical equivalents. In one embodiment, the invention provides a method of treating an autoimmune disease by administering pertussis toxin to the individual. In another embodiment, the autoimmune disease is multiple sclerosis. In another embodiment, the invention provides a method of treating a neurodegenerative disease such as Alzheimer's disease or Parkinson's disease by administering pertussis toxin, or a derivative, analog, salt or pharmaceutical equivalent.
Claims14
A method of treating and/or ameliorating the effects of multiple sclerosis (MS), and/or systemic lupus erythematosus (SLE) in a human subject with MS or SLE, comprising:
- providing a composition comprising pertussis toxin (PTx) comprising subunits A and B;
- and
- administering a therapeutically effective dosage of the composition comprising pertussis toxin (PTx) comprising subunits A and B to the human subject.
Dependencies are inferred from the claim text.