Barrier layer

An implantable barrier layer device, comprising:

• a biocompatible mesh structure;
• and
• an anti-adhesion barrier layer and a biological oil barrier layer formed on at least a portion of the mesh structure so that the anti-adhesion barrier layer covers a first side of the mesh but does not completely cover the other side of the mesh, wherein the anti-adhesion barrier layer comprises a heat-cured fish oil that is hydrolysable by lipase, wherein the fish oil comprises eicosapentaenoic acid and docosahexanoic acid, wherein the cured oil comprises fatty acids and glycerides, wherein two or more of the fatty acids are cross-linked to each other by ester bonds in a substantially random configuration, wherein the anti-adhesion barrier layer is in a solid state that is flexible, and wherein the anti-adhesion barrier layer is bio-absorbable and degrades into non-inflammatory substances, and
• wherein the biological oil barrier layer comprises uncured fish oil.

A barrier layer device, comprising:

• a biocompatible mesh structure;
• and
• a barrier layer formed on at least a portion of the mesh structure;
• wherein the barrier layer comprises cured fish oil and uncured fish oil, wherein the cured fish oil is hydrolysable by lipase and comprises fatty acids and glycerides, wherein two or more of the fatty acids are cross-linked to each other by ester bonds in a substantially random configuration so that the barrier layer provides a biological oil barrier and a physical anti-adhesion barrier, and wherein the barrier layer degrades into non-inflammatory substances.

An implantable medical device, comprising:

• a surgical mesh structure;
• a bioabsorbable anti-adhesion barrier layer formed on at least a portion of the surgical mesh structure, wherein the barrier layer comprises a cured fish oil, wherein the fish oil comprises eicosapentaenoic acid and docosahexanoic acid, wherein the cured fish oil comprises fatty acids and glycerides, wherein the cured fish oil is hydrolysable by lipase and contains cross-linking between two or more fatty acids of the fish oil, wherein cross-linking in the anti-adhesion barrier layer is provided by ester and peroxide bonds, and wherein the anti-adhesion barrier layer is solid but flexible and serves as a physical barrier, and wherein the anti-adhesion barrier layer degrades into non-inflammatory substances comprising free fatty acids;
• and
• a biological oil barrier layer supported by the anti-adhesion barrier layer, wherein the biological oil barrier layer comprises uncured fish oil.