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US 9,801,903 B2Granted
Targeting cancer with metabolic therapy and hyperbaric oxygen
AssigneeUniversity of South Florida
InventorsDominic Paul D'Agostino, Angela Marie Poff, Patrick Arnold
Life of this patent
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Abstract
A method of treating cancer using ketogenic diet, while concurrently subjecting the patient to a hyperbaric, oxygen-enriched environment. Optionally, the hyperbaric, oxygen-enriched environment is 100% oxygen at 2.5 ATA absolute. The treatment may further include administering at least 10% ketone supplementation, such as acetoacetate, adenosine monophosphate kinase, 1,3-butanediol, or ketone ester, to the patient.
Claims6
A method of reducing metastasis in cancer, comprising:
- administering to an animal with a metastatic cancer a therapeutically effective amount of acetoacetate, 1,3-butanediol acetoacetate monoester, 1,3-butanediol acetoacetate diester, R,S-1,3-butanediol-diacetoacetate ester, R-1,3-butanediol diacetoacetate ester, or a combination thereof.
Dependencies are inferred from the claim text.