Compositions comprising S-adenosylmethionine and a gallic acid ester
AssigneeMethylation Sciences International SRL
InventorsDechi Guan, I. David MacDonald
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Abstract
Provided herein are compositions and formulations comprising S-adenosyl-L-methionine (“SAM-e” or “SAMe”) and one or more gallic acid esters. Also provided herein are methods for improving the delivery of SAMe. Compositions and formulations provided herein increase SAMe plasma concentrations and area under the curve (AUC) values. Also provided herein are methods of treating a disease or disorder in a subject by administering compositions or formulations comprising exogenous SAMe and one or more gallic acid esters.
Claims20
An oral composition comprising exogenous S-adenosylmethionine and at least one gallic acid ester selected from the group consisting of ethyl gallate, isoamyl gallate, propyl gallate, octyl gallate, methyl gallate, butyl gallate, and isobutyl gallate, wherein said composition does not comprise epigallocatechin gallate.
Dependencies are inferred from the claim text.