Dynamic bioactive nanofiber scaffolding
AssigneeMo-Sci Corporation
InventorsThomas E. Day, Steven B. Jung, Charanpreet S. Bagga
Life of this patent
Estimating the term…
Abstract
A resorbable bone graft scaffold material, including a plurality of overlapping and interlocking fibers defining a scaffold structure, plurality of pores distributed throughout the scaffold, and a plurality of glass microspheres distributed throughout the pores. The fibers are characterized by fiber diameters ranging from about 5 nanometers to about 100 micrometers, and the fibers are a bioactive, resorbable material. The fibers generally contribute about 20 to about 40 weight percent of the scaffold material, with the microspheres contributing the balance.
Claims10
A method for producing a resorbable, flexible bone graft scaffold material comprising:
- forming a plurality of resorbable fibers;
- interlinking the plurality of resorbable fibers to define a fabric having a plurality of open pores;
- and
- filling at least some of the open pores with bioactive, resorbable ceramic microspheres;
- wherein the fibers are characterized by fiber diameters substantially ranging from about 5 nanometers to about 10 micrometers;
- and
- wherein the microspheres are characterized by diameters ranging up to about 3 millimeters.
Dependencies are inferred from the claim text.