System and method for performing renal denervation verification
AssigneePacesetter, Inc.
InventorsEric S. Fain, Martin Cholette, Gary R. Dulak, Gene A. Bornzin, John W. Poore
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Abstract
A renal denervation feedback method is described that performs a baseline measurement of renal nerve plexus electrical activity at a renal vessel; denervates at least some tissue proximate the renal vessel after performing the baseline measurement; performs a post-denervation measurement of renal nerve plexus electrical activity at the renal vessel, after the denervating; and assesses denervation of the renal vessel based on a comparison of the baseline measurement and the post-denervation measurement of renal nerve plexus electrical activity at the renal vessel.
Claims14
A renal denervation feedback method comprising:
- performing a baseline measurement of intrinsic renal nerve plexus electrical activity at a renal vessel by monitoring compound action potentials including baseline afferent and efferent signals;
- denervating at least some tissue proximate the renal vessel after performing the baseline measurement;
- performing a post-denervation measurement of intrinsic renal nerve plexus electrical activity at the renal vessel by monitoring post-denervation compound action potentials including post-denervation afferent and efferent signals, after the denervating;
- assessing denervation of the renal vessel based on a comparison of the baseline measurement and the post-denervation measurement of renal nerve plexus electrical activity at the renal vessel;
- and
- determining the denervation is complete when the post-denervation compound action potentials include afferent signals below a threshold value.
A renal denervation feedback system comprising:
- at least one denervation member to denervate at least some tissue proximate the renal vessel;
- at least one measurement member to perform a baseline measurement of intrinsic renal nerve plexus electrical activity, including baseline afferent and efferent signals, at a renal vessel before denervation of at least some tissue proximate the renal vessel and to perform a post-denervation measurement of renal nerve plexus electrical activity, including post-denervation afferent and efferent signals, at the renal vessel after the denervation, the baseline and post-denervation measurements acquired by monitoring compound action potentials;
- and
- a denervation assessment module to assess denervation of the renal vessel based on a comparison of the baseline measurement and the post-denervation measurement of renal nerve plexus electrical activity at the renal vessel, wherein the denervation assessment module is configured to determine the denervation is complete when the post-denervation compound action potentials include afferent signals below a threshold value.
Dependencies are inferred from the claim text.