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US 9,801,573 B2Granted
Endoscope system, processor device, and method for operating endoscope system
AssigneeFUJIFILM Corporation
InventorTakaaki Saito
Life of this patent
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Abstract
A color image sensor captures a reflected image of narrowband light having a wavelength range in which an extinction coefficient varies with a change in an oxygen saturation level of hemoglobin in blood. Thereby a first blue signal, a first green signal, and a first red signal are obtained. The color image sensor captures a reflected image of white light. Thereby a second blue signal, a second green signal, and a second red signal are obtained. Only an oxygen saturation level, out of two or more types of biological functional information including a blood volume and the oxygen saturation level, is obtained based on the first blue signal, the second green signal, and the second red signal. The oxygen saturation level is visualized to produce an oxygen saturation image.
Claims13
An endoscope system comprising:
- a light source that sequentially applies white light and blue narrowband light in which extinction coefficient varies significantly in accordance with a change in an oxygen saturation level of hemoglobin in blood, to a subject;
- a color image sensor that receives an imaging reflection light from the subject illuminated by the blue narrowband light in a first frame to obtain a first image signal, and receives an imaging reflection light from the subject illuminated by the white light in a second frame to obtain a second image signal, and a third image signal, the first image signal corresponding to first reflection light including a first wavelength range in a blue region, an extinction coefficient varying in accordance with an oxygen saturation level of hemoglobin in blood in the first wavelength range, the second image signal corresponding to second reflection light including a second wavelength range in a red region, the third image signal being used for standardizing the first and the second image signals, the third image signal corresponding to third reflection light including a third wavelength range in a green region, the third wavelength range differing from the first and the second wavelength ranges;
- a processing circuitry configured for:
- obtaining a first standardization signal ratio and a second standardization signal ratio, the first standardization signal ratio being obtained by standardizing the first image signal with the third image signal, the second standardization signal ratio being obtained by standardizing the second image signal with the third image signal;
- calculating the oxygen saturation level from a combination of the first and second standardization signal ratios with referring to a correlation stored in a memory, the correlation being a predefined relation between the oxygen saturation and the combination of the first and second standardization signal ratios;
- and
- producing an oxygen saturation image in which the oxygen saturation level is visualized in pseudo color, with referring to a color table stored in a memory, and
- a display that displays the oxygen saturation image.
5 more elements
An endoscope system comprising:
- a light source that sequentially applies white light and blue narrowband light in which extinction coefficient varies significantly in accordance with a change in an oxygen saturation level of hemoglobin in blood, to a subject;
- a color sensor that receives an imaging reflection light from the subject illuminated by the blue narrowband light in a first frame to obtain a first image signal, and receives an imaging reflection light from the subject illuminated by the white light in a second frame to obtain a second image signal, and a third image signal, the first image signal corresponding to first reflection light including a first wavelength range in a blue region, an extinction coefficient varying in accordance with an oxygen saturation level of hemoglobin in blood in the first wavelength range, the second image signal corresponding to second reflection light including a second wavelength range in a red region, the third image signal being used for standardizing the first and the second image signals, the third image signal corresponding to third reflection light including a third wavelength range in a green region, the third wavelength range differing from the first and the second wavelength ranges;
- a processing circuitry configured for:
- obtaining a first standardization signal ratio and a second standardization signal ratio, the first standardization signal ratio being obtained by standardizing the first image signal with the third image signal, the second standardization signal ratio being obtained by standardizing the second image signal with the third image signal;
- producing an oxygen saturation image with the use of a first correlation between the first standardization signal ratio and first color information and for producing a blood volume image with the use of a second correlation between the second standardization signal ratio and second color information, the oxygen saturation level being visualized in pseudo color with referring to a color table stored in a memory, the blood volume being visualized in the blood volume image;
- and
- calculating the oxygen saturation level from a combination of the first and second standardization signal ratios with referring to a correlation stored in a memory;
- the correlation being a predefined relation between the oxygen saturation and the combination of the first and second standardization signal ratios;
- a display device that displays the oxygen saturation image and the blood volume image.
6 more elements
An endoscope system comprising:
- a light source that sequentially applies white light and blue narrowband light in which extinction coefficient varies significantly in accordance with a change in an oxygen saturation level of hemoglobin in blood, to a subject;
- a color sensor that receives an imaging reflection light from the subject illuminated by the blue narrowband light in a first frame to obtain a first image signal, and receives an imaging reflection light from the subject illuminated by the white light in a second frame to obtain a second image signal and a third image signal, the first image signal corresponding to first reflection light including a first wavelength range in a blue region, an extinction coefficient varying in accordance with an oxygen saturation level of hemoglobin in blood in the first wavelength range, the third image signal corresponding to third reflection light including a third wavelength range in a green region, the third image signal being used for standardizing the first image signal, the third wavelength range differing from the first wavelength range;
- a processing circuitry configured for:
- obtaining a first standardization signal ratio and a second standardization signal ratio, the first standardization signal ratio being obtained by standardizing the first image signal with the third image signal, the second standardization signal ratio being obtained by standardizing the second image signal with the third image signal;
- producing an oxygen saturation image with the use of a first correlation between the first standardization signal ratio and first color information, the oxygen saturation level being visualized in pseudo color with referring to a color table stored in a memory;
- and
- calculating the oxygen saturation level from a combination of the first and second standardization signal ratios with referring to a correlation stored in said memory;
- the correlation being a predefined relation between the oxygen saturation and the combination of the first and second standardization signal ratios;
- and
- a display device that displays the oxygen saturation image.
7 more elements
A processor device used with an endoscope device for receiving and imaging reflection light from a subject illuminated with a light source, the light source sequentially applying white light and blue narrowband light in which extinction coefficient varies significantly in accordance with a change in an oxygen saturation level of hemoglobin in blood, to said subject, to obtain a first image signal, and receives an imaging reflection light from the subject illuminated by the white light in a second frame to obtain a second image signal, and a third image signal, the first image signal corresponding to first reflection light including a first wavelength range in a blue region, an extinction coefficient varying in accordance with an oxygen saturation level of hemoglobin in blood in the first wavelength range, the second image signal corresponding to second reflection light including a second wavelength range in a red region, the third image signal being used for standardizing the first and the second image signals, the third image signal corresponding to third reflection light including a third wavelength range in a green region, the third wavelength range differing from the first and the second wavelength ranges;
- the processor device further configured for:
- obtaining a first standardization signal ratio and a second standardization signal ratio, the first standardization signal ratio being obtained by standardizing the first image signal with the third image signal, the second standardization signal ratio being obtained by standardizing the second image signal with the third image signal;
- calculating the oxygen saturation level from a combination of the first and second standardization signal ratios with referring to a correlation stored in a memory;
- producing an oxygen saturation image in which the oxygen saturation level is visualized in pseudo color with referring to a color table stored in said memory;
- wherein a correlation between a first color information and a combination of the first and second standardization signal ratios to produce the oxygen saturation image;
- wherein the correlation is a predefined relation between the oxygen saturation and the combination of the first and second standardization signal ratios, and
- receiving the first image signal, second image signal and third image signal from the endoscope device.
4 more elements
A method for operating an endoscope system comprising the steps of:
- sequentially applying white light and blue narrowband light in which extinction coefficient varies significantly in accordance with a change in an oxygen saturation level of hemoglobin in blood, to a subject;
- applying illumination light from a light source;
- obtaining first to third image signals, the first to the third image signals being obtained by receiving and imaging reflection light from a subject with an imaging device, the first image signal corresponding to first reflection light including a first wavelength range in a blue region, an extinction coefficient varying significantly in accordance with an oxygen saturation level of hemoglobin in blood in the first wavelength range, the second image signal corresponding to second reflection light including a second wavelength range in a red region, the third image signal being used for standardizing the first and the second image signals, the third image signal corresponding to third reflection light including a third wavelength range in a green region, the third wavelength range differing from the first and the second wavelength ranges;
- obtaining a first standardization signal ratio and a second standardization signal ratio, the first standardization signal ratio being obtained by standardizing the first image signal with the third image signal, the second standardization signal ratio being obtained by standardizing the second image signal with the third image signal;
- producing an oxygen saturation image based on the first to the third image signals with the use of an oxygen saturation image generator, the oxygen saturation level being visualized in the oxygen saturation image;
- and
- displaying the oxygen saturation image on a display device,
- wherein the image generator uses a correlation between a first color information and a combination of the first and second standardization signal ratios to produce the oxygen saturation image;
- wherein the correlation is a predefined relation between the oxygen saturation and the combination of the first and second standardization signal ratios.
6 more elements
Dependencies are inferred from the claim text.