Method and device for indicating differentiation between tissues

A device for indicating differentiation between tissues of a subject, comprising:

• a computer configured to identify multiple tissues in a subject and, for each tissue among said multiple tissues, executing a simulation comprising a random scan sequence, wherein a magnetic resonance scan of each tissue is simulated with a selected parameter of the scan being randomly varied so as to have different parameter values and in which, as a result of the different parameter values, the respective tissue is given a magnetization vector in the simulation;
• said computer being configured to calculate dependent on the respective magnetization vectors for each of the multiple tissue, a differentiation-indicating value between each pair of tissues among said multiple tissues;
• said computer being configured to simulate a pair of brightness curves for each said pair of tissues among said multiple tissues and to use the respective differentiation-indicating values to differentiate between each pair of brightness curves, and thereby obtaining a differentiation for each pair of brightness curves;
• and
• said computer being configured to select, based on said differentiation, a magnetic resonance fingerprinting (MRF) protocol for scanning the multiple tissues, and to make said MRF protocol available from the computer in electronic form with a format configured to operate a magnetic resonance imaging apparatus in order to execute the selected MRF protocol.