US 9,791,441 B2Granted

Device and method for the detection of particles

AssigneeClondiag GmbH

InventorsEugen Ermantraut, Ralf Bickel, Torsten Schulz, Thomas Ullrich, Jens Tuchscheerer

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Abstract

The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or second surface. The invention also relates to corresponding methods for the detection of particles.

Claims15

Dependent claims

A device, comprising:

a detection chamber that receives a sample comprising multiple labelled particles,
an actuator that displaces some of the multiple labelled particles from the detection chamber comprising a first surface and a second surface opposite to the first surface and comprising an area made of an elastically deformable material so that only a first subset of the multiple labelled particles remains in the chamber as a result of the elastically deformable material,
a detector including an optical system that detects particles of the first subset of labelled particles,
a processor that determines, based on the detected particles, a value indicative of the number of particles of the first subset of particles and to determine the number or abundance of particles in the sample based on the number of particles of the proper subsets.

1 more element

Dependencies are inferred from the claim text.

Facts

Application: 13/919,524Filed 17 Jun 2013 · continuation
Priority: DE 10 2005 052 7524 Nov 2005
Published: US 2013/0295657 A17 Nov 2013
Granted: 17 Oct 2017
Term ends: Not estimatedThe source records don’t support an estimate.

Classification18 codes

G01N 33/56966
For microorganisms, e.g. protozoa, bacteria, viruses: animal cells
B01F 31/31
Comprising a receptacle to only a part of which the shaking, oscillating, or vibrating movement is imparted: using receptacles with deformable…
B01F 31/86
Mixing by means of high-frequency vibrations above one kHz, e.g. ultrasonic vibrations: with vibration of the receptacle or part of it
B01F 33/30
Other mixers; Mixing plants; Combinations of mixers: micromixers

Family

PCT/EP2006/068153Parent of this continuation · filed 6 Nov 2006
Application13/274,175Parent of this continuation · filed 14 Oct 2011
US 8,040,494 B2Parent of this continuation · filed 18 Oct 2011
US 2013/0295657 A1Pre-grant publication · published 7 Nov 2013
US 8,467,039 B2Parent of this continuation
Application12/092,422Parent of this continuation
US 2009/0079963 A1Published application
US 2012/0088252 A1Published application
US 9,791,441 B2This patent

From the US filing history. Foreign family members aren’t listed.