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US 9,790,473 B2Granted
Human Ebola virus species and compositions and methods thereof
AssigneeThe United States of America, as represented by the Secretary, Department of Health and Human Services
InventorsJonathan S. Towner, Stuart T. Nichol, James A. Comer, Thomas G. Ksiazek, Pierre E. Rollin
Life of this patent
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Abstract
Compositions and methods including and related to the Ebola Bundibugyo virus (EboBun) are provided. Compositions are provided that are operable as immunogens to elicit and immune response or protection from EboBun challenge in a subject such as a primate. Inventive methods are directed to detection and treatment of EboBun infection.
Claims15
An immunogenic composition comprising:
- a protein consisting of an amino acid sequence of:
- at least 70 contiguous residues of the amino acid sequence of SEQ ID NO:
- 9(GP);
- and
- an immunostimulatory adjuvant present in an amount that increases an immune response to the immunogenic composition in a subject.
2 more elements
An immunogenic composition comprising:
- a protein comprising an amino acid sequence at least 75% identical to SEQ ID NO:
- 9;
- and
- an immunostimulatory adjuvant present in an amount that increases an immune response to the immunogenic composition in a subject.
1 more element
Dependencies are inferred from the claim text.