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US 9,790,465 B2Granted
Spheroid cell culture well article and methods thereof
AssigneeCorning Incorporated
InventorsScott Matthew Bennett, Brian Robb Douglass, Paul Ernest Gagnon, Jr., Gregory Roger Martin, Paul Michael Szlosek, Allison Jean Tanner
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Abstract
A spheroid cell culture article including: a frame having a chamber including: an opaque side wall surface; a top aperture; a gas-permeable, transparent bottom; and optionally a chamber annex surface and second bottom, and at least a portion of the transparent bottom includes at least one concave arcuate surface, is disclosed. Methods of making and using the article are also disclosed.
Claims22
A cell culture article comprising:
- a chamber comprising:
- an opaque side wall;
- a top aperture;
- and
- a gas-permeable, liquid impermeable bottom comprising at least one concave surface, wherein at least a portion of the bottom is transparent and wherein at least a portion of the bottom comprises a low-adhesion or no-adhesion material in or on the at least one concave surface.
2 more elements
Dependencies are inferred from the claim text.