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US 9,790,278 B2Granted
Anti-B7-H6 antibody, fusion proteins, and methods of using the same
AssigneeTrustees of Dartmouth College
InventorsCharles L. Sentman, Tong Zhang
Life of this patent
Estimating the term…
Abstract
Antibodies, chimeric antigen receptors, and bispecific T-cell engagers having specificity for B7-H6 and methods for using the same in the diagnosis and treatment of disorders associated with B7-H6 expression are provided.
Claims17
A chimeric antigen receptor comprising:
- (a) an antigen binding fragment of an antibody that specifically binds to B7 homolog 6 (B7-H6),
- (b) a transmembrane region, and
- (c) an intracellular T-cell receptor signaling domain.
Dependencies are inferred from the claim text.