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US 9,790,213 B2Granted
Imidazoles for the treatment and prophylaxis of respiratory syncytial virus infection
AssigneeHoffmann-La Roche Inc.
InventorsLu Gao, Chungen Liang, Lisha Wang, Hongying Yun
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Abstract
The invention provides novel compounds having the general formula: wherein R1, R2, R3 and Q are as described herein, compositions including the compounds and methods of using the compounds.
Claims8
Compounds of formula (I)
- wherein
- R1 is hydrogen, C1-6alkyl, C1-6alkoxy or halogen;
- R2 is hydrogen, C1-6alkyl or halogen;
- provided that R1 and R2 are not hydrogen simultaneously;
- R3 is
- wherein R4 is C1-6alkoxy, C1-6alkoxycarbonyl, carboxy or halogen;
- R5 is hydrogen, C1-6alkyl or C1-6alkoxy;
- R6 is hydrogen or C1-6alkoxy;
- Q is
- wherein R7 is hydrogen, C1-6alkyl, carboxy, hydroxy-CH2— or halogen;
- R8 is hydrogen or C1-6alkyl;
- R9 is C1-6alkyl;
- or pharmaceutically acceptable salts thereof.
10 more elements
Dependencies are inferred from the claim text.