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US 9,790,186 B2Granted
Composition and method for prevention, mitigation or treatment of an enteropathogenic bacterial infection
AssigneeTrustees of Dartmouth College
InventorsF. Jon Kull, Ronald K. Taylor, Gordon W. Gribble, Evans O. Onyango, Anne R. Kelley
Life of this patent
Estimating the term…
Abstract
Bicyclic compounds for decreasing the expression of bacterial virulence factors thereby preventing, mitigating, or treating bacterial infection are provided.
Claims9
A compound or a hydrate, isomer or pharmaceutically acceptable salt thereof having the structure:
- wherein
- R1 is selected from the group consisting of C1-C6 alkyl, C1-C6 alkenyl;
- R2 is H, alkenyl, or oxo;
- n is 1-6;
- and dashed lines a-e represent bonds that are independently present or absent and wherein dashed lines a-e are all present or all absent or dashed lines a, b and c are present and e and d are absent.
2 more elements
A compound selected from the group consisting of:
- and pharmaceutically acceptable salts thereof.
Dependencies are inferred from the claim text.