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US 9,789,201 B2Granted
Self-assembling complex for targeting chemical agents to cells
AssigneeCedars-Sinai Medical Center
InventorLali K. Medina-Kauwe
Life of this patent
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Abstract
The present invention relates to a complex that can be injected into the body to hone in on target cells to deliver molecules. In one embodiment, the invention provides a drug delivery system that includes components that self-assemble into one targeted conjugate. In another embodiment, the invention includes a targeted carrier protein and a nucleic acid sequence non-covalently linked to one or more drugs.
Claims33
A method of treating a disease in an individual, comprising:
- administering a therapeutically effective amount of a drug delivery molecule to the individual, the drug delivery molecule comprising:
- a polypeptide sequence adapted to target and penetrate a type of cell,
- a nucleic acid sequence bound to the polypeptide sequence via electrostatic interactions, and
- a chemical agent non-covalently linked to the nucleic acid sequence.
1 more element
Dependencies are inferred from the claim text.