Diagnosis and treatment of prostate cancer
AssigneeThe Research Foundation for The State University of New York
InventorsManya Dhar-Mascareno, Eduardo J. Mascareno
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Abstract
The methods of the present disclosure are directed toward methods of diagnosis and treatment of cancer in a subject. The present disclosure provides methods of diagnosing abnormal cells in a subject by measuring the level of Hexim-1 in a sample from the subject, where elevated levels of Hexim-1 indicate abnormal cells. This disclosure further provides methods of treating cancer or hyperplasia, comprising administering to a subject in need thereof a therapeutically effective amount of Hexim-1 or an activator of Hexim-1 expression or activity.
Claims5
A method of diagnosing and treating prostate cancer in a patient, which comprises:
- obtaining a sample from a human patient;
- detecting whether Hexim-1 is present in the sample by contacting the sample with an antibody of Hexim-1;
- diagnosing the patient with prostate cancer when a level of Hexim-1 in the sample is detected;
- and
- administering to the patient a therapeutically effective amount of Hexim-1, an activator of Hexim-1 expression or activity, or an inhibitor of Hexim-1 phosphorylation.
Dependencies are inferred from the claim text.