Vegetation water composition for treatment of inflammatory skin conditions

A method for treating a person suffering from an inflammatory skin condition presenting as a discrete or generalized area of skin lesions, comprising:

• identifying a person suffering from such an inflammatory skin condition that has proven refractory to treatment with immunosuppressives or glucocorticoids, and
• orally administering to said person, an effective amount of a pharmaceutical composition selectively enriched for hydroxytyrosol, whereby the pharmaceutical composition is produced by (i) obtaining vegetation water from olives, (ii) adding acid to the vegetation water thereby producing acidified vegetation water, (iii) incubating the acidified vegetation water for a period until the weight ratio of hydroxytyrosol to oleuropein is between 4:1 and 200:1, thereby producing incubated acidified vegetation water, and (iv) adding 90 to 360 mg of solid olive extract to the incubated acidified vegetation water thereby producing the pharmaceutical composition, wherein the pharmaceutical composition is orally administered on a daily basis over a period of at least three months so as to reduce the area of the discrete or generalized skin lesions by at least 60%.