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AssigneesFederal State Budgetary Scientific Institution “Research Institute for Cardiology”, National Research Tomsk Polytechnic University, Limited Liability Company “Nanocor”
InventorsShamil′ D. Akhmedov, Sergej A. Afanasiev, Victor D. Filimonov, Pavel S. Postnikov, Marina E. Trusova, Rostislav S. Karpov
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The invention relates to the medicine, namely to an agent for reducing the cholesterol and triglycerides in the blood plasma. The agent claimed comprises a nanocomposite that is a carbon-containing nanoparticles coated with the organic alkyl functional groups representing the residuals —C4H9, —C6H11, —C8H15, —C10H21, —C16H33, —C18H35. These groups are deposited by the covalent modification using diazonium salts of the general formula XC6H4N2+Y−, where X is the alkyl residual —C4H9, —C6H11, —C8H15, —C10H21, —C16H33, or C18H35, Y is the anion HSO4−, Cl−, BF4− or TsO−. The invention provides an effective reduction of cholesterol and triglyceride presented in the blood plasma.
An agent for reducing cholesterol and triglycerides in blood plasma, the agent comprising a nanocomposite of carbon containing nanoparticles and organic residues deposited on the nanoparticles, the organic residues comprising an alkyl group selected from the group consisting of —C4H9, —C6H11, —C8H15, —C10H21, —C16H33, and —C18H35 deposited by covalent modification of the nanoparticles by diazonium salts with a general formula XC6H4N2+Y−, wherein X is the alkyl group selected from the group consisting of —C4H9, —C6H11, —C8H15, —C10H21, —C16H33, and —C18H35, and wherein Y is an anion HSO4−, Cl−, BF4− or TsO−.
Dependencies are inferred from the claim text.