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US 9,789,109 B2Granted
Modified albumin microbubble and method of making the same
AssigneeNational Taiwan University of Science and Technology
InventorsAi-Ho Liao, Chih-Hung Wang
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Abstract
A modified microbubble is provided. The modified microbubble includes an albumin microbubble and a plurality of chitosan oligosaccharide lactates. The albumin microbubble includes an albumin shell and a gas core inside the albumin shell. The plurality of chitosan oligosaccharide lactates is connected to an outer surface of the albumin shell.
Claims5
A method of making a modified microbubble, comprising:
- providing an albumin microbubble, comprising:
- supplying gas into an albumin solution;
- and
- sonicating the albumin solution to form an albumin shell encompassing the gas to form the albumin microbubble;
- and
- connecting a plurality of chitosan oligosaccharide lactates to the albumin microbubble in an environment with a temperature of 0-10° C. to form the modified microbubble.
3 more elements
Dependencies are inferred from the claim text.