Methods and compositions for treating microbial infection using pyrroloquinone
AssigneeHelperby Therapeutics Limited
InventorsYanmin Hu, Anthony M. R. Coates
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Abstract
A pharmaceutical composition can include dyclonine hydrochloride and 4-methyl-1-(2-phenylethyl)-8-phenoxy-2,3-dihydro-1H-pyrrolo[3,2-c]-quinoline.
Claims4
A pharmaceutical composition comprising dyclonine hydrochloride and 4-methyl-1-(2-phenylethyl)-8-phenoxy-2,3-dihydro-1 H-pyrrolo[3,2-c]-quinoline, wherein the combination of dyclonine hydrochloride and 4-methyl-1-(2-phenylethyl)-8-phenoxy-2,3-dihydro-1 H-pyrrolo[3,2-c]-quinoline shows a synergistic antimicrobial activity against log phase and/or latent microorganisms.
A pharmaceutical composition comprising dyclonine hydrochloride and 4-methyl-1-(2-phenylethyl)-8-phenoxy-2,3-dihydro-1 H-pyrrolo[3,2-c]-quinoline, wherein the combination of dyclonine hydrochloride and 4-methyl-1-(2-phenylethyl)-8-phenoxy-2,3-dihydro-1 H-pyrrolo[3,2-c]-quinoline shows a synergistic activity against stationary phase S. aureus.
A pharmaceutical composition comprising a combination of dyclonine or a pharmaceutically acceptable salt and/or solvate thereof, and 4-methyl-1-(2-phenylethyl)-8-phenoxy-2,3-dihydro-1 H-pyrrolo[3,2-c]-quinoline, or a pharmaceutically acceptable salt and/or solvate thereof, wherein the combination shows a synergistic antimicrobial activity against log phase and/or latent microorganisms.
A pharmaceutical composition comprising a combination of dyclonine or a pharmaceutically acceptable salt and/or solvate thereof, and 4-methyl-1-(2-phenylethyl)-8-phenoxy-2,3-dihydro-1 H-pyrrolo[3,2-c]-quinoline, or a pharmaceutically acceptable salt and/or solvate thereof, wherein the combination shows a synergistic activity against stationary phase S. aureus.
Dependencies are inferred from the claim text.