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US 9,789,078 B2Granted
Method of topically treating actinic keratosis with ingenol mebutate cycle therapy
AssigneeLEO Laboratories Limited
InventorKirsten Norrelund
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AssigneeLEO Laboratories Limited
InventorKirsten Norrelund
Estimating the term…
The present invention relates to cyclic or repeated use of the ingenol mebutate for topical treatment of actinic keratosis lesions. Generally speaking, the present invention comprises a first ingenol mebutate treatment cycle and a second ingenol mebutate treatment cycle, wherein the first treatment cycle topically treats a treatment area with a topical gel formulated with ingenol mebutate at a selected dosage strength for a specified treatment regimen, and the second ingenol mebutate treatment cycle comprises topically re-treating the treatment area with the same topical ingenol mebutate gel for the same specified treatment regimen, if following the first treatment cycle, the treatment area failed to clear or failed to remain clear of AK lesions. The present invention further relates to spot or individual lesion therapy in the treatment area following the topical bi-cyclic therapy with ingenol mebutate.
A method for topically treating a subject diagnosed with actinic keratosis lesions in a treatment area, said method comprising administering topically more than one treatment cycle of ingenol mebutate to the treatment area, each treatment cycle separated by an interval without treatment.
A method for topically treating a subject diagnosed with actinic keratosis lesions in a treatment area on the face or scalp of the subject, said method comprising:
Dependencies are inferred from the claim text.