Bolus dose of hydroxycitric acid with glycerol
AssigneeGlykon Technologies Group, LLC
InventorsDallas L. Clouatre, Daniel E. Clouatre, Brad J. Douglass
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Abstract
A method of delivering a daily dose of hydroxycitric acid in the form of a salt as a single bolus that is as effective or more so than the same amount of active delivered via two or three administrations (b.i.d. or t.i.d.) using current delivery modalities. The method reduces the rate of occurrence of common adverse events with hydroxycitric acid salts, and reduces the occurrence of reverse effects on diets high in fat and/or alcohol. The method improves the uptake of the active compound thereby reducing the dose required.
Claims3
A method of delivering a pharmaceutical composition consisting essentially of:
- orally administering a liquid sealed dosage of a hydroxycitrate salt in combination with glycerol and a coffee extract, wherein the hydroxycitrate salt is administered in amount of 3.0 g to 4.5 g±20%, and the glycerol is present in an amount in a range of from 1.0 g to 4.0 g±20%, and
- wherein the liquid sealed dosage is prepared by mixing glycerol in water wherein the glycerol is present in an amount of about 1 to 3 parts by volume and the water is present in an amount of about 3 to 1 parts by volume to create a solution;
- dissolving hydroxycitrate salt in the solution wherein the hydroxycitrate salt is present in a concentration ranging from about 1.1 to 1.7 molar dosage.
Dependencies are inferred from the claim text.