Carrier for oromucosal administration of physiologically active substances
AssigneeInstar Technologies A.S.
InventorsDenisa Stranska, Adela Klabanova, Pavel Dolezal, Petr Vrbata, Pavel Berka, Marie Musilova
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Abstract
The present disclosure relates to a carrier for oromucosal, especially sublingual administration of physiologically active substances, especially of medicinal drugs, which consists of at least one elastic layer (1) of polymer nanofibers workable according to the shape of the selected wall of mouth cavity to which it should be applied and in this elastic layer (1) of polymer nanofibers a drug and/or other physiologically active substance are deposited in a releasable manner.
Claims9
A carrier for oromucosal administration of physiologically active substances, comprising:
- at least one flexible layer of polymer nanofibres having a first side and a second side, comprising a releasable drug and/or other physiologically active substance, and the polymer nanofibers comprise an adhesive adapted for contact and adhesion with a sublingual surface of a mouth cavity of a subject on an adhesion location;
- and
- a covering layer that overlaps a first side of the at least one flexible layer of polymer nanofibres, and the covering layer is adapted to prohibit leaching of the releasable drug and/or other physiologically active substance from the at least one flexible layer of polymer nanofibres to outside of the adhesion location and into the mouth cavity,
- wherein the at least one flexible layer of polymer nanofibres is produced by needleless electrostatic spinning, and wherein the releasable drug and/or other physiologically active substance is released at the adhesion location.
Dependencies are inferred from the claim text.