Methods and devices for drug delivery to ocular tissue using microneedle
AssigneesGeorgia Tech Research Corporation, Emory University
InventorsMark R. Prausnitz, Henry F. Edelhauser, Samirkumar Rajnikant Patel
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Abstract
Methods and devices are provided for targeted administration of a drug to a patient's eye. In one embodiment, the method includes inserting a hollow microneedle into the sclera of the eye at an insertion site and infusing a fluid drug formulation through the inserted microneedle and into the suprachoroidal space of the eye, wherein the infused fluid drug formulation flows within the suprachoroidal space away from the insertion site during the infusion. The fluid drug formulation may flow circumferentially toward the retinochoroidal tissue, macula, and optic nerve in the posterior segment of the eye.
Claims9
A method, comprising:
- inserting a microneedle into a suprachoroidal space of an eye at an insertion site without the microneedle penetrating through the choroid, the microneedle comprising a drug formulation which comprises a drug;
- and
- forming a drug depot at the insertion site in the suprachoroidal space for controlled release of the drug to an ocular tissue.
Dependencies are inferred from the claim text.