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US 9,788,953 B2Granted
System and method of attaching soft tissue to an implant
AssigneePurdue Research Foundation
InventorsThomas J. Webster, Venu Perla
Life of this patent
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Abstract
One embodiment of the present invention is directed to compositions and methods for enhancing attachment of soft tissues to a metal prosthetic device. In one embodiment a construct is provided comprising a metal implant having a porous metal region, wherein said porous region exhibits a nano-textured surface.
Claims23
An implant comprising:
- a porous metal region, wherein said porous metal region is reticulated and/or has pores with a diameter of 10 to 800 μm;
- one or more layers on the porous metal region selected from the group consisting of:
- a calcified material layer or calcification-inducing layer coating said porous metal region or in contact with a nanomaterial coating layer or nanosurface roughness formed on the porous metal region, if present;
- and
- a bioactive scaffold layer comprising a biocompatible polymer matrix and a bioactive agent, wherein at least a portion of the scaffold layer is in contact with the calcified material layer or calcification-inducing layer, where said calcified material layer or calcification-inducing layer is present.
2 more elements
Dependencies are inferred from the claim text.