Compositions and methods for detecting human Pegivirus 2 (HPgV-2)
AssigneesAbbott Laboratories, The Regents of the University of California
InventorsCharles Chiu, Deanna Lee, Michael Berg, George Dawson, Kelly Coller, Kevin Cheng, John Hackett, Matthew Frankel, Kenn Forberg
Life of this patent
Estimating the term…
Abstract
Provided herein are compositions, methods, and kits for detecting human Pegivirus 2 (HPgV-2). In certain embodiments, provided herein are HPgV-2 specific nucleic acid probes and primers, and methods for detecting HPgV-2 nucleic acid. In other embodiments, provided herein are HPgV-2 immunogenic composition compositions, methods of treating a subject with immunogenic HPgV-2 peptides, and methods of detecting HPgV-2 subject antibodies in a sample.
Claims11
A method of detecting human Pegivirus 2 (HPgV-2) specific antibodies in a subject comprising:
- a) contacting a sample from a subject suspected of containing an antibody to HPgV-2 with a HPgV-2 peptide, wherein said peptide specifically binds said antibody to form a complex, and
- wherein said HPgV-2 peptide comprises an amino acid sequence selected from the group consisting of SEQ ID NOs:86-99 and 100-218;
- and
- b) detecting whether said antibody is present in said sample by detecting binding between said antibody and said peptide.
Dependencies are inferred from the claim text.