Antibody to genetic products differentially expressed in tumors and the use thereof
AssigneeGanymed Pharmaceuticals AG
InventorsOzlem Tureci, Ugur Sahin, Michael Koslowski, Stephan Fritz, Harald-Gerhard Geppert
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Abstract
According to the invention, gene products expressed in a tumor-associated manner and the nucleic acids coding therefor were identified. The invention relates to the therapy and diagnosis of diseases wherein said gene products expressed in a tumor-associated manner are aberrantly expressed. The invention also relates to proteins, polypeptides and peptides which are expressed in a tumor associated manner and to nucleic acids coding therefor.
Claims12
A purified antibody or an antigen binding fragment thereof that binds to a tumor-associated antigen selected from the group consisting of:
- a tumor-associated antigen comprising the amino acid sequence of SEQ ID NO:
- 16;
- wherein binding of said antibody to said tumor-associated antigen is prevented by glycosylation at a glycosylation site of said tumor-associated antigen.
Dependencies are inferred from the claim text.