# US 9,775,531 B2 · Sensor device, processing device, and measurement system for acquiring a biopotential > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,775,531 B2 - Document ID: US9775531B2 - Status: Granted - Kind: B2 - Application number: 13/946,176 - Filed: 2013-07-19 - Published: 2013-11-14 - Granted: 2017-10-03 - Earliest claimed: 2010-06-09 - Assignees: Techmedic Development International B.V. - Applicants: Techmedic Development International B.V. - Inventors: Rutger Alexander Brest Van Kempen; Alexander Adriaan Huntelerslag - Web page: https://patentgrep.com/patent/US9775531B2 ## CPC - A61B 5/308: for electrocardiography [ECG] - A61B 5/7203: {for noise prevention, reduction or removal} - A61B 2562/182: Electrical shielding, e.g. using a Faraday cage - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) ## Abstract A measurement system for acquiring biopotentials is provided, which comprises a sensor device and a processing device, which are electrically connected to cooperate during use. The measurement system may be capable of simultaneous measurement of biopotentials by the sensor device and wireless transmission of amplified biopotentials by the processing device, and may be provided with means for preventing the measurements from being disturbed by the transmissions. Also disclosed are (i) a sensor device for measuring a biopotential having at least one sensor with a measurement electrode for measuring the biopotential at a measurement portion of a body and (ii) a processing device for processing biopotentials that has at least one sensor input for receiving the amplified biopotentials measured by a sensor of the sensor device. ## Claims ### Claim 1 A device for measuring a biopotential Vp, comprising at least one sensor comprising: (i) a measurement electrode for measuring the biopotential Vp at a measurement portion of a body, (ii) a measurement connection for a lead, (iii) a first reference connection for receiving a reference potential Vref, and (iv) a differential amplifier connected to the measurement connection and arranged for generating an amplified biopotential VP at a differential amplifier output by amplification of an electrical potential difference between the measured biopotential Vp and the reference potential Vref, wherein the differential amplifier comprises a first operational amplifier with an input connected to the reference potential Vref, a second operational amplifier with an input connected to the reference potential Vref and a further input connected to an output of the first operational amplifier, wherein a second operational amplifier output is connected in parallel with the measured biopotential Vp, forming a feedback loop with the first operational amplifier, and wherein the differential amplifier further comprises a low-pass filter arranged to filter the biopotential Vp prior to entering the first operational amplifier, and a high-pass filter in combination with the second operational amplifier. ### Claim 2 (depends on 1) The device according to claim 1, further comprising a reference electrode with a second reference connection, arranged for supplying the reference potential Vref to a reference portion of the body. ### Claim 3 (depends on 1) The device according to claim 1, wherein the at least one sensor further comprises a power connection for receiving a power signal for feeding the differential amplifier. ### Claim 4 (depends on 3) The device according to claim 3, wherein the measurement connection, the first reference connection, and the power connection are integrally formed and combined with the lead. ### Claim 5 (depends on 1) The device according to claim 1, wherein the differential amplifier comprises at least one RF-radiation hardened operational amplifier arranged for shielding the at least one sensor from external EM RF fields. ### Claim 6 A processing device for processing biopotentials, comprising: (i) at least one sensor input for receiving an analog amplified biopotential VP measured by a sensor, (ii) a reference voltage source for generating a reference potential Vref, (iii) an amplifier power source for generating a power signal, and (iv) at least one reference output and at least one power output, which are arranged for outputting the reference potential Vref to a differential amplifier and the power signal to the sensor, the differential amplifier comprises a first operational amplifier with an input connected to the reference potential Vref, a second operational amplifier with an input connected to the reference potential Vref and a further input connected to an output of the first operational amplifier, wherein a second operational amplifier output is connected in parallel with the measured biopotential Vp, forming a feedback loop with the first operational amplifier, and wherein the differential amplifier further comprises a low-pass filter arranged to filter the biopotential Vp prior to entering the first operational amplifier, and a high-pass filter in combination with the second operational amplifier. ### Claim 7 (depends on 6) The processing device according to claim 6, further comprising a second reference output arranged for supplying the reference potential Vref to a reference electrode. ### Claim 8 (depends on 6) The processing device according to claim 6, wherein the sensor input, a first reference output, and the power output are integrally formed as a sensor connection for each sensor. ### Claim 9 (depends on 6) The processing device according to claim 6, further comprising a communication unit arranged for wireless transmission of the amplified biopotential VP by EM RF fields. ### Claim 10 (depends on 9) The processing device according to claim 9, wherein the EM RF fields have frequencies in GSM frequency bands. ### Claim 11 A measurement system for acquiring an amplified biopotential VP, comprising: (a) a sensor device comprising at least one sensor comprising (i) a measurement electrode for measuring the biopotential Vp at a measurement portion of a body, (ii) a measurement connection for a lead, (iii) a first reference connection for receiving a reference potential Vref, and (iv) a differential amplifier connected to the measurement connection and arranged for generating an amplified biopotential VP at a differential amplifier output by amplification of an electrical potential difference between the measured biopotential Vp and the reference potential Vref, and (b) a processing device comprising (i) at least one sensor input for receiving an analog amplified biopotential VP measured by a sensor, (ii) a reference voltage source for generating a reference potential Vref, (iii) an amplifier power source for generating a power signal, and (iv) at least one reference output and at least one power output, which are arranged for outputting the reference potential Vref and the power signal to a differential amplifier of the sensor, respectively, wherein at least one sensor of the sensor device is electrically connected with at least one sensor input of the processing device by a lead during use, and wherein the differential amplifier comprises a first operational amplifier with an input connected to the reference potential Vref, a second operational amplifier with an input connected to the reference potential Vref, wherein a further input of the second operational amplifier is connected to an output of the first operational amplifier, wherein a second operational amplifier output is connected in parallel with the measured biopotential Vp, forming a feedback loop with the first operational amplifier, and wherein the differential amplifier further comprises a low-pass filter arranged to filter the biopotential prior to entering the first operational amplifier, and a high-pass filter in combination with the second operational amplifier. ### Claim 12 (depends on 11) The measurement system according to claim 11, arranged for simultaneous measurement of a biopotential Vp by the sensor device and wireless transmission of the analog amplified biopotential VP by the processing device by EM RF fields. ### Claim 13 (depends on 11) The measurement system according to claim 11, arranged for receiving biopotential measurement instructions by the communication unit of the processing device by EM RF fields, and for measuring the biopotential Vp according to the biopotential measurement instructions. ### Claim 14 A method of acquiring an amplified biopotential VP with a measurement system comprising (i) a sensor device comprising at least one sensor with a differential amplifier, and (ii) a processing device comprising at least one sensor input, wherein during use, the at least one sensor is electrically connected with the at least one sensor input, wherein the differential amplifier comprises a first operational amplifier with an input connected to the reference potential Vref, a second operational amplifier with an input connected to the reference potential Vref, wherein a further input of the second operational amplifier is connected to an output of the first operational amplifier, wherein a second operational amplifier output is connected in parallel with the measured biopotential Vp, forming a feedback loop with the first operational amplifier, and wherein the differential amplifier fluffier comprises a low-pass filter arranged to filter die biopotential Vp prior to entering the first operational amplifier, and a high-pass filter in combination with the second operational amplifier, the method comprising measuring a biopotential Vp at a measurement portion of a body using the at least one sensor by (a) providing a reference potential Vref to a reference portion of the body; (b) providing the measured biopotential Vp and the reference potential Vref to the differential amplifier; and (c) generating the amplified biopotential VP by the differential amplifier based on a potential difference between the measured biopotential Vp and the reference potential Vref. ### Claim 15 (depends on 14) The method according to claim 14, comprising simultaneously measuring the biopotential Vp using the at least one sensor, and wireless transmission of the analog amplified biopotential VP by RF EM fields, using the processing device comprising a communication unit.