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US 9,757,435 B2Granted
Clostridium histolyticum enzymes and methods for the use thereof
AssigneeEndo Global Ventures
InventorWayne K. Herber
Life of this patent
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Abstract
The invention relates to recombinant nucleic acid and polypeptides encoding collagenase I and collagenase II, methods for the preparation thereof and methods for the use thereof. The invention also encompasses methods related to releasing a composition comprising collagenase prior to therapeutic administration.
Claims12
A recombinant nucleic acid molecule comprising;
- a) a polynucleotide having the nucleic acid sequence of SEQ ID NO:
- 1 or the complement of SEQ ID NO:
- 1, and
- b) a heterologous regulatory sequence operably linked to the polynucleotide.
1 more element
Dependencies are inferred from the claim text.