Flexible poly-p-(phenyleneethynylene)s with controlled conjugation length and biodegradable conjugated polymers for target organelle specific labeling and drug delivery

Abstract

A novel monomer design for the synthesis of PPE-type polymers containing conjugated segments of well-defined length connected by flexible linkers under Sonogashira reaction conditions is presented. The resulting polymers retain the photophysical properties of a fully conjugated PPE. The extent of incorporation of the flexible units along the backbone is governed by the comonomer feed ratio and can be varied in a statistically predictable fashion.

Dependencies are inferred from the claim text.