# US 9,753,147 B2 · Desktop open-gantry spect imaging system

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- Number: US 9,753,147 B2
- Document ID: US9753147B2
- Status: Granted
- Kind: B2
- Application number: 14/975,772
- Filed: 2015-12-19
- Published: 2016-04-28
- Granted: 2017-09-05
- Earliest claimed: 2015-04-12
- Assignees: Parto Negar Persia Co.
- Applicants: Parto Negar Persia Co.
- Inventors: Navid Zeraatkar; Mohammad Hossein Farahani; Mohammad Reza Ay; Saeid Sarkar
- Web page: https://patentgrep.com/patent/US9753147B2

## CPC

- G01T 1/1648: {Ancillary equipment for scintillation cameras, e.g. reference markers, devices for removing motion artifacts, calibration devices (adapted for flow studies G01T1/1647)}
- A61B 6/037: {Emission tomography}
- A61B 6/06: Diaphragms
- A61B 6/4208: {characterised by using a particular type of detector}
- A61B 6/44: {Constructional features of apparatus for radiation diagnosis}
- A61B 6/508: {for non-human patients}
- G21K 1/02: using diaphragms, collimators
- G01T: MEASUREMENT OF NUCLEAR OR X-RADIATION (radiation analysis of materials, mass spectrometry G01N23/00; tubes for determining the presence, intensity, density or energy of radiation or particles H01J47/00)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G21K: HANDLING OF PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES

## Abstract

An open-gantry structure of SPECT imaging system for scanning human small organs or small animals and method for preparing the system is disclosed. The system contains an imaging desk that one or multiple detector heads are rotated around the object to be scanned while tilted under the imaging desk and dedicated image reconstruction algorithm was developed for the system in case of applying single pinhole collimator.

## Claims

### Claim 1

A single-photon emission computed tomography (SPECT) imaging system comprising:
an imaging desk located in a first plane; and
a head located below the imaging desk and configured to rotate around an object to be imaged, wherein:
the head is coupled to a motor and includes a detector and a collimator,
the head is configured to rotate in a second plane parallel to the first plane, and
the head is tilted under the imaging desk with a tilt angle being in a range of 0° to 90°.

### Claim 2 (depends on 1)

The SPECT imaging system according to claim 1, wherein the system has a desktop open-gantry structure.

### Claim 3 (depends on 1)

The SPECT imaging system according to claim 1, wherein the collimator is selected from a group consisting of parallel-hole, pinhole, multi-pinhole, and combination thereof.

### Claim 4 (depends on 1)

The SPECT imaging system according to claim 1, wherein the collimator includes a pinhole collimator.

### Claim 5 (depends on 1)

The SPECT imaging system according to claim 1, wherein the collimator is made of lead, tungsten or gold.

### Claim 6 (depends on 1)

The SPECT imaging system according to claim 1, wherein the detector is selected from a group consisting of simple monolithic scintillation crystal coupled to Photomultiplier Tubes (PMTs), a pixelated scintillating crystal coupled to Position-Sensitive PMTs (PSPMTs), a monolithic/pixelated crystal coupled to photodiodes, or a solid-state detector.

### Claim 7 (depends on 1)

The SPECT imaging system according to claim 1, wherein the detector includes a monolithic scintillation crystal coupled to PMTs.

### Claim 8 (depends on 1)

The SPECT imaging system according to claim 1, wherein whole parts of the object to be imaged are placed on the imaging desk.

### Claim 9 (depends on 1)

The SPECT imaging system according to claim 1, wherein a first portion of the object to be imaged is placed on the imaging desk and a second portion of the object is placed beneath the imaging desk.

### Claim 10

A method for data acquisition in a SPECT imaging system, wherein the SPECT imaging system has an open-gantry structure and includes an imaging desk and a head located below the imaging desk and configured to rotate around an object to be imaged, the method comprising:
placing the object on or beneath the imaging desk located in a first plane;
rotating the head around the object while the head is tilted underneath the imaging desk;
acquiring a plurality of projection views of the object; and
storing the acquired projection views, wherein:
rotating the head around the object includes rotating the head in a second plane spaced apart from the first plane and parallel to the first plane.

### Claim 11 (depends on 10)

The method according to claim 10, wherein the head includes a detector and a collimator.

### Claim 12 (depends on 11)

The method according to claim 11, wherein the collimator is selected from a group consisting of parallel-hole, pinhole, multi-pinhole and combination thereof.

### Claim 13 (depends on 11)

The method according to claim 11, wherein the collimator includes a pinhole collimator.

### Claim 14 (depends on 11)

The method according to claim 11, wherein the detector is selected from a group consisting of simple monolithic scintillation crystal coupled to Photomultiplier Tubes (PMTs), a pixelated scintillating crystal coupled to Position-Sensitive PMTs (PSPMTs), a monolithic/pixelated crystal coupled to photodiodes, or a solid-state detector.

### Claim 15 (depends on 11)

The method according to claim 11, wherein the detector includes a monolithic scintillation crystal coupled to PMTs.

### Claim 16 (depends on 10)

The method according to claim 10, wherein the object includes a human organ.

### Claim 17 (depends on 10)

The method according to claim 10, wherein the object includes a part of human body or an animal.

### Claim 18 (depends on 10)

The method according to claim 10, wherein the object is placed beneath the imaging desk.

### Claim 19 (depends on 10)

The method according to claim 10, wherein the head is tilted under the imaging desk with a tilt angle, and the tilt angle is between 0° to 90°.

### Claim 20

A method of obtaining a 3-D map of activity concentration in a SPECT imaging system, wherein the SPECT imaging system has an open-gantry structure and includes an imaging desk and a head located below the imaging desk and configured to rotate around an object to be imaged, the method comprising:
placing the object on or beneath the imaging desk resting in a first plane;
rotating the head around the object while the head is tilted underneath the imaging desk;
acquiring a plurality of 1-dimensional or 2-dimensional projection views of the object;
storing the plurality of projection views; and
performing a tomographic reconstruction algorithm for calculation of a 3-D map of activity concentration from the plurality of projection views, wherein:
rotating the head around the object includes rotating the head around the object in a second plane parallel to the first plane.
