# US 9,752,214 B2 · Titanium alloy

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- Number: US 9,752,214 B2
- Document ID: US9752214B2
- Status: Granted
- Kind: B2
- Application number: 13/983,005
- Filed: 2012-01-31
- Published: 2013-11-21
- Granted: 2017-09-05
- Earliest claimed: 2011-01-31
- Assignees: Nippon Piston Ring Co., Ltd.; National University Corporation Saitama University
- Applicants: Shunsuke Takeguchi; Yoshiki Ishikawa; Takasumi Kubo; Shin Ishida; Hiroki Takahashi; Masafumi Morita; Masahito Miki
- Inventors: Shunsuke Takeguchi; Yoshiki Ishikawa; Takasumi Kubo; Shin Ishida; Hiroki Takahashi; Masafumi Morita; Masahito Miki
- Web page: https://patentgrep.com/patent/US9752214B2

## CPC

- C22C 14/00: Alloys based on titanium
- A61L 27/06: Titanium or titanium alloys
- A61L 31/022: {Metals or alloys}
- C22C 27/02: Alloys based on vanadium, niobium, or tantalum
- C22F 1/183: {of titanium or alloys based thereon}
- Y10T 428/12: All metal or with adjacent metals
- C22C: ALLOYS (treatment of alloys C21D, C22F)
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)
- C22F: CHANGING THE PHYSICAL STRUCTURE OF NON-FERROUS METALS AND NON-FERROUS ALLOYS (surface treatment of metallic material involving at least one process provided for in class C23 and at least one process covered by this subclass, C23F17/00)
- Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

## Abstract

A titanium alloy includes 15 to 27 atomic % (at %) of tantalum (Ta) and 0 to 8 at % of tin (Sn), the balance being titanium (Ti) and unavoidable impurities, when the entire amount of the titanium alloy is taken as 100 at %. Therefore, the titanium alloy provided has characteristics suitable for medical device materials, biocompatible materials, etc.

## Claims

### Claim 1

A titanium alloy for a living body, consisting of:
15 to 27 atomic % (at %) of tantalum (Ta); and
1 to 8 at % of tin (Sn) with the balance being titanium (Ti) and unavoidable impurities, when an entire amount of the titanium alloy is taken as 100 at %;
wherein the titanium alloy has a Young's modulus of 40 Gpa or lower and a tensile strength of 800 MPa or larger and
a value obtained by dividing the total atomic % of the tantalum and the tin by the total atomic % of the titanium and the unavoidable impurities is within a range of 0.34 to 0.36 within which the titanium alloy has both at once a maximum tensile strength and a minimum Young's modulus.

### Claim 2 (depends on 1)

The titanium alloy according to claim 1, wherein a saturation magnetic flux density in a B-H curve obtained by a VSM method is 5.0×10−4 T (tesla) or lower when a strength of a magnetic field is 4.0×105 A/m.

### Claim 3 (depends on 1)

The titanium alloy according to claim 1, having an elastic deformation strain of 1.0% or larger.

### Claim 4 (depends on 1)

The titanium alloy according to claim 1, wherein in a three-point bending test performed under measurement conditions in which a distance between two supporting members is 20 mm and a diameter d of a pointed end of each of the supporting members and a pressing member is 5 mm, when the pressing member presses the titanium alloy formed into a wire having a diameter φ of 0.5 mm to a pressing depth of 4 mm at a pressing rate of 1 mm/minute and then a load is released, an amount of recovery of the wire is 60% or higher.

### Claim 5 (depends on 1)

The titanium alloy according to claim 1, wherein a degree of cell injury when a metal ion concentration measured by ICP emission spectrometry is 64 ppm or less is less than 10%.

### Claim 6 (depends on 1)

The titanium alloy according to claim 1, wherein the titanium alloy is formed into a medical guidewire, a medical delivery wire, a medical stent, a medical clip, an aneurysm embolization coil or a vein filter, or a dental cleanser, a dental reamer, a dental file or an orthodontic wire.

### Claim 7 (depends on 6)

The titanium alloy according to claim 6, having a maximum outer diameter of 0.005 mm to 1 mm.

### Claim 8 (depends on 1)

The titanium alloy according to claim 1, wherein the tantalum content is 22 to 24 at %.
