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AssigneeModern Meadow, Inc.
InventorsFrancoise Suzanne Marga, Brendan Patrick Purcell, Gabor Forgacs, Andras Forgacs
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Edible microcarriers, including microcarrier beads, microspheres and microsponges, appropriate for use in a bioreactor to culture cells that may be used to form a comestible engineered meat product. For example, the edible microcarriers described herein may include porous microcarriers that may be used to grow cells (e.g., smooth muscle cells) and may be included with the cells in the final engineered meat product, without requiring modification or removal of the cells from the microcarriers. In a particular example, the edible microcarriers may be formed of cross-linked pectin, such as pectin-thiopropionylamide (PTP), and RGD-containing polypeptide, such as thiolated cardosin A. Methods of forming edible microcarriers, methods of using the edible microcarriers to make engineered meat, and engineered meat including the edible microcarriers are also described herein.
A method of forming an edible and animal-product-free microcarrier for use as part of an engineered meat product, the method comprising:
A method of forming an edible and animal-product-free microcarrier for use as part of an engineered meat product, the method comprising:
A method of forming an edible and animal-product-free microcarrier for use in forming an engineered meat product, the method comprising:
An edible microcarrier that is free of animal products and that is configured for culturing muscle cells to form an engineered meat product, the edible microcarrier having a body comprising a hydrogel of cross-linked pectin and an RGD-containing polypeptide, wherein the body is between about 3 mm and about 0.05 mm in diameter, wherein the pectin comprises thiol-modified pectin (PTP).
An edible microcarrier that is free of animal products and that is configured for culturing muscle cells to form an engineered meat product, the edible microcarrier having a body comprising a hydrogel of cross-linked pectin and an RGD-containing polypeptide, wherein the body is between about 3 mm and about 0.05 mm in diameter, wherein the RGD-containing polypeptide comprises a cardosin.
An edible microcarrier that is free of animal products and that is configured for culturing muscle cells to form an engineered meat product, the edible microcarrier having a body comprising a hydrogel of thiol-modified pectin and cardosin, wherein the body is between about 3 mm and about 0.05 mm in diameter.
Dependencies are inferred from the claim text.