# US 9,751,834 B2 · Oxygenated amino- or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives and their medical use

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 9,751,834 B2
- Document ID: US9751834B2
- Status: Granted
- Kind: B2
- Application number: 14/403,168
- Filed: 2012-05-25
- Published: 2015-10-08
- Granted: 2017-09-05
- Earliest claimed: 2011-05-26
- Assignees: Gri Bio, Inc.
- Applicants: Georg Schlechtingen; Hans-Joachim Knölker; Tim Friedrichson; Gary Jennings; Tobias Braxmeier
- Inventors: Georg Schlechtingen; Hans-Joachim Knölker; Tim Friedrichson; Gary Jennings; Tobias Braxmeier
- Web page: https://patentgrep.com/patent/US9751834B2

## CPC

- C07C 309/14: containing amino groups bound to the carbon skeleton
- C07D 223/04: with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A61K 31/205: Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
- A61P 29/00: Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P 35/00: Antineoplastic agents
- A61P 37/00: Drugs for immunological or allergic disorders
- C07D 207/02: with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D 221/00: Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07C: ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07D: HETEROCYCLIC COMPOUNDS (macromolecular compounds C08)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

The present invention relates to oxygenated amino or ammonium-containing sulfonic acid, phosphonic acid and carboxylic acid derivatives, in particular the compounds of formula 1, 2, 3, 4, 5 or 6, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.

## Claims

### Claim 1

A compound of the following formula 1a:
or a pharmaceutically acceptable salt or solvate thereof.

### Claim 2 (depends on 1)

A pharmaceutical composition comprising the compound of claim 1 and a pharmaceutically acceptable excipient.