# US 9,750,951 B2 · Liquid type plasma for preventing or treating cancer

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- Number: US 9,750,951 B2
- Document ID: US9750951B2
- Status: Granted
- Kind: B2
- Application number: 14/982,948
- Filed: 2015-12-29
- Published: 2016-10-13
- Granted: 2017-09-05
- Earliest claimed: 2015-04-09
- Assignees: Ajou University Industry-Academic Cooperation Foundation
- Applicants: Ajou University Industry-Academic Cooperation Foundation
- Inventors: Chul Ho Kim; Sun Yong Kim
- Web page: https://patentgrep.com/patent/US9750951B2

## CPC

- A61N 1/44: Applying ionised fluids {(ion generators H01J37/00)}
- A61K 33/00: Medicinal preparations containing inorganic active ingredients
- H05H 1/24: Generating plasma {(nuclear fusion reactors G21B1/00; gas-filled discharge reactors H01J37/32)}
- H05H 1/247: {using discharges in liquid media}
- H05H 2240/20: Non-thermal plasma
- H05H 2245/32: Surgery, e.g. scalpels, blades or bistoury; Treatments inside the body
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- H05H: PLASMA TECHNIQUE (apparatus or processes specially adapted for producing X-rays H05G2/00); PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS

## Abstract

The present invention relates to a method for preparing a plasma for preventing or treating a cancer. Also, the present invention relates to a liquid type plasma for preventing or treating a cancer prepared by treating the plasma and a pharmaceutical composition for preventing or treating a cancer comprising the same. The plasma and the liquid type plasma according to the present invention can effectively induce cancer cell death without a surgical operation or in a treatment process after a surgical operation, thereby being useful as a novel therapeutic agent and method for a cancer.

## Claims

### Claim 1

An anticancer agent comprising a liquid type plasma prepared by a method comprising:
1) filling a plasma generator with a carrier gas;
2) generating a plasma by supplying a voltage of 0.5 kV to 20 kV to the carrier gas; and
3) irradiating a medium with the generated plasma.

### Claim 2

A method for treating a cancer, the method comprising:
1) filling a plasma generator with a carrier gas;
2) generating a plasma by supplying a voltage of 0.5 kV to 20 kV to the carrier gas;
3) obtaining a liquid type plasma by irradiating a medium with the generated plasma; and
4) treating a subject with the liquid type plasma.

### Claim 3 (depends on 2)

The method of claim 2, wherein the cancer is at least one selected from the group consisting of thyroid cancer, oral cavity cancer, pharynx cancer, liver cancer, lung cancer, melanoma, and head and neck cancer.

### Claim 4 (depends on 2)

The method of claim 2, wherein the carrier gas is selected from helium, oxygen or a combination thereof.

### Claim 5 (depends on 2)

The method of claim 2, wherein the treatment is a treatment after a cancer operation.