# US 9,750,938 B2 · Visualization of biological environment impact on implanted therapy

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- Number: US 9,750,938 B2
- Document ID: US9750938B2
- Status: Granted
- Kind: B2
- Application number: 14/630,211
- Filed: 2015-02-24
- Published: 2015-09-17
- Granted: 2017-09-05
- Earliest claimed: 2014-03-11
- Assignees: Cardiac Pacemakers, Inc.
- Applicants: Cardiac Pacemakers, Inc.
- Inventors: David J. Ternes; Brian D. Soltis; LeAnne M. Eberle
- Web page: https://patentgrep.com/patent/US9750938B2

## CPC

- A61N 1/36142: {for improving safety}
- A61N 1/37247: {User interfaces, e.g. input or presentation means}
- A61N 1/3614: {based on impedance measurement}
- A61N 1/365: controlled by a physiological parameter, e.g. heart potential {(evoked response A61N1/371)}
- A61N 1/378: Electrical supply
- A61N 2001/083: {Monitoring integrity of contacts, e.g. by impedance measurement}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

An implantable medical device (IMD) system communicates to a user information regarding the surrounding biological environment and the influence of that surrounding biological environment on IMD functionality. This influence can be static or dynamic. Providing information on the biological environment can assist the user in determining therapy parameters for an individual patient with an IMD.

## Claims

### Claim 1

A method, comprising:
measuring a parameter according to a programmed schedule, the parameter associated with a biological environment, for a system including an implantable medical device (IMD) configured for delivering electrical stimulation therapy;
determining an upper limit of the therapy that can be delivered by the IMD based on the measured parameter, including determining potentiality for nerve damage from therapy delivery by the IMD based on the parameter; and
displaying the limit to a user using an interface of an external device, including displaying the potentiality for nerve damage from therapy delivery by the IMD, the external device configured to communicate with the IMD.

### Claim 2 (depends on 1)

The method of claim 1, wherein measuring a parameter associated with biological environment includes sensing impedance for at least a portion of a lead system connected to the IMD.

### Claim 3 (depends on 2)

The method of claim 2, wherein determining a limit of the therapy includes determining voltage compliance based on the sensed impedance and calculating a limit of electric current level that can be delivered by the IMD based on the determined voltage compliance.

### Claim 4 (depends on 3)

The method of claim 3, further comprising using a color code to display the calculated limit.

### Claim 5 (depends on 3)

The method of claim 3, wherein displaying the limit includes displaying a color palette with selections for programming parameters for delivering therapy.

### Claim 6 (depends on 2)

The method of claim 2, further comprising:
determining charge density based on the sensed impedance;
determining potential for nerve damage from therapy delivery by the based on the determined charge density; and
displaying the determined potential for nerve damage using the interface.

### Claim 7 (depends on 2)

The method of claim 2, further comprising:
determining maximum allowable programmed frequency of pulse delivery based on the sensed impedance load and time duration of recharge; and
displaying the maximum allowable programmed frequency of pulse delivery to a user using the interface.

### Claim 8 (depends on 2)

The method of claim 2; further comprising:
determining charge used over time based on the sensed impedance and settings input by the user;
measuring battery capacity for the IMD;
calculating device longevity for the IMD based on the determined charge and battery capacity; and
displaying the device longevity to a user using the interface.

### Claim 9 (depends on 8)

The method of claim 8, wherein the displaying includes displaying an interactive longevity display including a projected estimate.

### Claim 10 (depends on 1)

The method of claim 1, wherein delivering electrical stimulation therapy includes delivering neurostimulation therapy.

### Claim 11 (depends on 1)

The method of claim 1, wherein delivering electrical stimulation therapy includes delivering cardiac rhythm management (CRM) therapy.

### Claim 12 (depends on 1)

The method of claim 1, wherein measuring a parameter includes sensing a parameter related to intrinsic cardiac function for a patient.

### Claim 13 (depends on 12)

The method of claim 12, further comprising:
determining a combination of input parameters for a therapy that increase a likelihood of undesired amounts of cardiac pacing for the patient based in part on the sensed parameter; and
displaying the combination of input parameters to a user using the interface.

### Claim 14 (depends on 13)

The method of claim 13, wherein the displaying includes providing real-time information on a lower rate limit (LRL) that will lead to decreased RV-only pacing.

### Claim 15 (depends on 13)

The method of claim 13, wherein the displaying includes providing real-time information on an AV delay that will lead to decreased RV-only pacing.
