# US 9,750,901 B2 · Dry powder drug-dosing device

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- Number: US 9,750,901 B2
- Document ID: US9750901B2
- Status: Granted
- Kind: B2
- Application number: 14/125,936
- Filed: 2012-06-08
- Published: 2014-05-22
- Granted: 2017-09-05
- Earliest claimed: 2011-06-13
- Assignees: Shanghai Xiuxin Chenpon Pharmaceutical Technology Co., Ltd.
- Applicants: Lan Chen; Dizheng Du; Lei Xu
- Inventors: Lan Chen; Dizheng Du; Lei Xu
- Web page: https://patentgrep.com/patent/US9750901B2

## CPC

- A61M 15/0065: {Inhalators with dosage or measuring devices (A61M15/0028 takes precedence; dosage devices incorporated in aerosol cans B65D83/52)}
- A61M 15/0006: {using rotating means}
- A61M 15/005: {the dosages being arranged on a cylindrical surface}
- A61M 2202/062: Desiccants
- A61M 2202/064: Powder
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

A dry powder drug-dosing device comprises a flow passage member (10), a drug powder storage container (19), and a drug-dosing metering component. A drug powder storage container (19), an annular manual rotation portion (3) and a rotational slide passage (23) are disposed on the outer surface of the housing. A sliding block (26) is disposed at an inner side of the annular manual rotation portion (3) A stirring gear (28) disposed on a transmission sleeve (27) is fit with the raised vibration tooth (21), so as to form a vibration component for enabling an outlet of the inverted conical drug powder storage container (19) to generate vibration. The dry powder drug-dosing device is applicable to the inhalation administration of various medicines in the form of dry powder.

## Claims

### Claim 1

A dry powder drug-dosing device, at least comprising a flow passage member, a drug powder storage container and a drug-dosing metering component, and said flow passage member containing a mouthpiece and a flow passage element, the dry powder drug-dosing device characterized by:
a housing constituted by an upper body and a lower body;
an inverted conical drug powder storage container disposed in an upper part of the housing;
an annular manual rotation portion disposed outside the upper part of the housing;
a rotational slide passage disposed on an outer surface of the upper part of the housing and a sliding block disposed at an inner side of the annular manual rotation portion correspondingly;
a first elastic member disposed in a cavity between the annular manual rotation portion and the upper part of the housing;
a gas inlet disposed at an end of the rotational slide passage;
the flow passage member disposed in the housing;
the mouthpiece disposed on an outside of the housing and a mouthpiece cap disposed on the outside of the mouthpiece;
a head end of said flow passage element connecting to the gas inlet, a tail end of the flow passage element connecting to the mouthpiece via an air channel, and a horizontal portion of the flow passage member having an opening as a drug inlet;
a drug-dosing metering component disposed below the inverted conical drug powder storage container; and
said flow passage element connected to the gas inlet, the drug-dosing metering component and the mouthpiece in sequence via the air channel.

### Claim 2 (depends on 1)

The dry powder drug-dosing device according to claim 1, wherein said rotational slide passage circuit comprises an upper slide passage and a lower slide passage which are parallel to each other, and a first lifting slide passage and a second lifting slide passage connected to head and tail ends of the upper slide passage and the lower slide passage; said annular manual rotation portion is configured to rotate in a restricted angle and ascend or descend at designated positions on the upper body under the guidance, limitation and effects of the upper slide passage, lower slide passage, the first lifting slide passage, the second lifting slide passage, the sliding block and the first elastic member.

### Claim 3 (depends on 2)

The dry powder drug-dosing device according to claim 2, wherein said restricted angle is 120°, said designated positions are the positions of head and tail ends of the upper and lower slide passages.

### Claim 4 (depends on 2)

The dry powder drug-dosing device according to claim 2, wherein at least one gas inlet is installed to pass through the housing of said lower slide passage.

### Claim 5 (depends on 1)

The dry powder drug-dosing device according to claim 1, wherein at least one gas inlet is installed to pass through the housing of said lower slide passage.

### Claim 6 (depends on 1)

The dry powder drug-dosing device according to claim 1, wherein said drug-dosing metering component comprises a ration drug-dosing plate with a central axis, a spring cover under the ration drug-dosing plate and a second elastic member positioned between the lower body and the spring cover;
a head end of said central axis passes through an upper part of the upper body and a triangle block is provided at a head end of the central axis;
a triangle hole is provided correspondingly in a center of said annular manual rotation portion;
a tail end of said central axis is connected to the lower body rotatably;
three drug-dosing cavities are distributed uniformly along a circumference on the side of the ration drug-dosing plate towards the inverted conical drug powder storage container;
the drug inlet of said flow passage element is arranged correspondingly to one of the three drug-dosing cavities distributed uniformly along the circumference.

### Claim 7 (depends on 6)

The dry powder drug-dosing device according to claim 6, wherein three elastic locating clips are distributed uniformly on the circumference of said ration drug-dosing plate; and three locating grooves are distributed correspondingly in an internal side of the lower body, said elastic locating clips match with the locating grooves to ensure the rotational range of the ration drug-dosing plate is one-third of the circumference every step and a definite signal of rotation in place is given to the user.

### Claim 8 (depends on 6)

The dry powder drug-dosing device according to claim 6, wherein said second elastic member is a spring.

### Claim 9 (depends on 6)

The dry powder drug-dosing device according to claim 6, wherein the upper part of said upper body is provided with a drying component consisting of a drying tube and granular desiccant therein; said drying tube has an opening in the direction identical to the outlet of the inverted conical drug powder storage container; said drying component and the inverted conical drug powder storage container are arranged in an included angle of 120° relative to the longitudinal central axis of the housing; the opening of said drying component or the outlet of said inverted conical drug powder storage container is arranged to be corresponding to two of three drug-dosing cavities distributed along a circumference of the ration drug-dosing plate of the drug-dosing metering component.

### Claim 10 (depends on 6)

The dry powder drug-dosing device according to claim 6, wherein a locking block is set on said annular manual rotation portion, when the mouthpiece cap is in covered status, said locking block cooperates with the mouthpiece cap to form an anti-misrotation mechanical structure, so as to prevent rotation between the annular manual rotation portion and the upper body.

### Claim 11 (depends on 10)

A process for inhalation administration using the dry powder drug-dosing device of claim 10, comprising steps of:
(A1) removing the mouthpiece cap and releasing the anti-misrotation mechanical structure on the annular manual rotation portion;
(B1) manually rotating the annular manual rotation portion counterclockwise to an extreme position of 120° to enable a first drug-dosing cavity of the ration drug-dosing plate in said drug-dosing metering component to receive a drug supplied from the inverted conical drug powder storage container; the annular manual rotation portion springing upward automatically and the air inlet opening to provide a condition for inhalation administration; meanwhile, the triangle block at the head end of the central axis of said drug-dosing metering component entering the triangle hole in the center of the annular manual rotation portion to provide a precondition for the next rotation of the ration drug-dosing plate;
(C1) manually rotating the annular manual rotation portion reversely to a reverse extreme position of 120°; and the first drug-dosing cavity with drug powder aiming at the drug inlet of the flow passage element to finish the drug supplying process;
(D1) inhaling the drug powder through the mouthpiece, wherein a gas enters the dry powder drug-dosing device from the air inlet and passes the flow passage element to reach the drug inlet, then delivers the drug powder from the first drug-dosing cavity of the ration drug-dosing plate to the patient's mouth via the mouthpiece, and the drug delivering process is finished;
(E1) manually pressing down the annular manual rotation portion to enable a second drug-dosing cavity of the ration drug-dosing plate in said drug-dosing metering component to aim at the drying component for drying and preparing for the next drug-filling; and
(F1) covering the mouthpiece cap and restoring the anti-misrotation mechanical structure on the annular manual rotation portion.

### Claim 12 (depends on 1)

The dry powder drug-dosing device according to claim 1, wherein said first elastic member is a spring.

### Claim 13 (depends on 1)

A process for inhalation administration using the dry powder drug-dosing device of claim 1, comprising steps of:
(A) removing the mouthpiece cap;
(B) manually rotating the annular manual rotation portion counterclockwise to an extreme position of 120°; the annular manual rotation portion springing upward automatically;
(C) manually rotating the annular manual rotation portion reversely to a reverse extreme position of 120°;
(D) inhaling the drug powder via the mouthpiece;
(E) pressing down the annular manual rotation portion manually; and
(F) covering the mouthpiece cap.

### Claim 14 (depends on 1)

The dry powder drug-dosing device of claim 1, wherein a vibrating drug-providing unit is equipped on the dry powder drug-dosing device;
said inverted conical drug powder storage container is disposed in the upper part of the housing;
an annular manual rotation portion is disposed outside the upper part of the housing;
a drug-dosing metering component comprising a center rotating axis and a ration drug-dosing plate is disposed under said inverted conical drug powder storage container;
said center rotating axis of said drug-dosing metering component is connected to said annular manual rotation portion by the meshing of triangle components, the block on the center rotating axis and a hole on the annular manual rotation portion;
a protruding vibration tooth is disposed at a lower part of said inverted conical drug powder storage container;
a transmission sleeve is disposed inside a lower end of said annular manual rotation portion;
an upper end of said transmission sleeve is fixedly connected to the annular manual rotation portion;
said transmission sleeve is coaxially set outside the central rotating axis;
a stirring gear is disposed at a lower end of said transmission sleeve; and
said protruding vibration tooth cooperates with the stirring Gear to form a vibration component to enable an outlet of the inverted conical drug powder storage container to vibrate.