# US 9,750,892 B2 · Medical injection device

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- Number: US 9,750,892 B2
- Document ID: US9750892B2
- Status: Granted
- Kind: B2
- Application number: 14/667,890
- Filed: 2015-03-25
- Published: 2015-07-16
- Granted: 2017-09-05
- Earliest claimed: 2010-12-31
- Assignees: Novo Nordisk A/S
- Applicants: Novo Nordisk A/S
- Inventors: Bo Radmer; Christian Plambech; Christian Hoejris Nielsen; Jesper Peter Windum; Tom Hede Markussen
- Web page: https://patentgrep.com/patent/US9750892B2

## CPC

- A61M 5/3202: {Devices for protection of the needle before use, e.g. caps (A61M5/50 takes precedence; protectors for sharps A61B50/3001)}
- A61M 5/002: {Packages specially adapted therefor, e.g. packages for syringes or needles or kits for diabetics}
- A61M 5/2466: {by piercing without internal pressure increase (A61M5/2429 takes precedence)}
- A61M 2005/3117: {Means preventing contamination of the medicament compartment of a syringe}
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

The present invention relates to injection devices for injecting a dose of a medicament. The injection device (100) incorporates a housing (101), a needle assembly (150) and a cover (200). The needle assembly (150) comprises an injection needle (152,153) accommodated in a needle container (151) having an opening which in a storage state of the injection device (100) is sealed by a film seal (155). The cover may include sections (201,202) arranged movable relative to the housing (101). The injection device (100) is so configured that upon movement of the cover sections (201,202) relative to the housing (101) the film seal (155) is changed from a sealing state to an unsealing state for shifting the injection device (100) into a ready-to-administer state.

## Claims

### Claim 1

An injection device (100,200; 100′; 100″) comprising:
a housing (101;101′,101″),
a cartridge (120; 120′;120″) arranged relative to the housing and defining a main axis, the cartridge (120;120′;120″) comprising an outlet covered by a cartridge septum adapted to be pierced by an injection needle (152,153;152′,153′;152″,153″) for establishing fluid communication with a cartridge interior and comprising a piston which is driveable along the main axis towards the outlet,
a piston driver (110;110′;110″) for engaging the piston and capable of being actuated for driving the piston in a distal direction towards the outlet,
a needle assembly (150;150′;150″) arranged at a distal end of the housing, the needle assembly comprising an injection needle (152,153;152′,153′;152″,153″) having front and rear sections for respectively penetrating skin of a subject user and for piercing the cartridge septum, the needle assembly (150;150′;150″) further comprising a needle container (151;151′;151″) accommodating the injection needle (152,153;152′,153′;152″,153″), the needle container (151;151′;151″) having an opening which in a storage state of the injection device (100,200;100′;100″) is sealed by a planar film seal (155;155′;155″) for maintaining the injection needle (152,153;152′,153′;152″,153″) in a sterile condition, and
a cover (200,170;170′;170″) arranged relative to the housing (101;101′,101″) and configured for relative movement, wherein, in the storage state of the injection device (100,200;100′;100″), the cover (200,170;170′;170″) is held relative to the housing (101,101′;101″) in a first relative orientation wherein the cover (200,170;170′;170″) at least partly covers the needle assembly (150;150′;150″),
wherein the injection device defines an unsealing member (115,206;115′;115″) which is adapted to cause the planar film seal (155;155′;155″) to change from a sealing state into an unsealing state by relative movement between the needle assembly (150;150′;150″)and the unsealing member (115,206;115′;115″), and
wherein relative movement between the cover (200,170;170′;170″) and the housing (101; 101′;101″) from the first relative orientation to a second relative orientation causes the planar film seal (155;155′;155″)to change from the sealing state to the unsealing state for shifting the injection device into a ready-to-administer state, the cover (200,170;170′;170″) being continuously coupled with the housing during said relative movement between the cover (200,170;170′;170″) and the housing (101) from the first relative orientation to the second relative orientation,
wherein the needle container (151;151′;151″)forms a body having a cup shaped form and defining a single sealed opening, wherein the single sealed opening is sealed by said planar film seal (155;155′;155″) to define a sealed chamber when the injection device (100,200;100′;100″) is in said storage state, the injection needle (152,153;152′,153′;152″,153″) being completely accommodated within the sealed chamber, and
wherein the cover (200,170;170′;170″) is configured for being separated from the housing (101;101″;101″) subsequent to the cover (200,170;170′;170″) being operated for changing the planar film seal (155;155′;155″) from the sealing state to the unsealing state but prior to actuation of the piston driver (110;110′;110″) for driving the piston towards the outlet, the cover (170;170′;170″) being configured for removing the needle container (151;151′;151″) from the injection needle (152,153;152′,153′;152″,153″) as the cover (170;170′;170″)is separated from the housing (101;101′;101″).

### Claim 2 (depends on 1)

The injection device as in claim 1, wherein the injection device (100,200;100′;100″) is configured to enable manual actuation of the piston driver (110;110′;110″) to drive the piston towards the outlet subsequent to the cover (200,170;170′;170″) being operated for changing the planar film seal (155;155′;155″)from the sealing state to the unsealing state.

### Claim 3 (depends on 1)

The injection device as in claim 1, wherein the cover (200,170;170′;170″)moves from a first position to a second position to cause the needle assembly (150;150′;150″) and the unsealing member (115;115′;115″)to move relatively to each other along said main axis to cause the planar film seal (155;155′;155″)to change from the sealing state to the unsealing state and wherein the movement of the cover (200,170;170′;170″) from the first position to the second position is different than a purely axial movement.

### Claim 4 (depends on 1)

The injection device as in claim 1, wherein the cover (200,170;170′;170″) moves from a first position to a second position to cause the planar film seal (155;155′;155″)to change from the sealing state to the unsealing state and wherein a force exerted by the user for operating the cover (200,170;170′;170″) relative to the housing (101) is transformed to a force of greater magnitude for effecting relative movement between the needle assembly (150;150′;150″)and the unsealing member (115;115′;115″) along said main axis.

### Claim 5 (depends on 1)

The injection device as in claim 1, wherein the cover (170;170′;170″)forms a cap which attaches to a distal end of the housing (101′;101″) when the injection device (100′;100″) is in the storage state.

### Claim 6 (depends on 5)

The injection device as in claim 5, wherein the cap (170′) and the housing (101′) forms a track and groove connection (102′,171′)and wherein a relative rotational movement between the cap (170′) and the housing (101′) is transformed into a linear movement defined by said track and groove connection for causing relative axial movement between the needle assembly (150′) and the unsealing member (115′).

### Claim 7 (depends on 5)

The injection device as in claim 5, wherein the injection device (100″) includes a pre-stressed spring (190″) which releases upon operation of the cap (170″) relative to the housing (101″), wherein the spring (190″), when released, drives the needle assembly (150″) and the unsealing member (115″) relative to each other for changing the planar film seal (155″) from the sealing state to the unsealing state.

### Claim 8 (depends on 1)

The injection device as in claim 1, wherein the cover (200,170) at least in part forms a packaging which in the storage state of the injection device (100,200) accommodates the housing (101) of the injection device (100,200).

### Claim 9 (depends on 8)

The injection device as in claim 8, wherein the cover (200,170) defines a first cover section (201) which swivels relative to the housing (101) along a second axis (204), the second axis being substantially orthogonal to the main axis.

### Claim 10 (depends on 9)

The injection device as in claim 9, wherein the first cover section (201) forms a lever arm which upon operation causes the needle assembly (150) and the unsealing member (115,206) to move relative to each other.

### Claim 11 (depends on 9)

The injection device as in claim 9, wherein the cover (200) further defines a second cover section (202) wherein the first and second cover sections forms cooperating shells for accommodating the housing (101) and the needle assembly (150).

### Claim 12 (depends on 1)

The injection device as in claim 1, wherein relative movement between the cover (200,170; 170′; 170″) and the housing (101;101′;101″) further causes the rear section of the injection needle (153;153′;153″) to pierce the cartridge septum.