# US 9,750,890 B2 · Mechanism for a drug delivery device

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- Number: US 9,750,890 B2
- Document ID: US9750890B2
- Status: Granted
- Kind: B2
- Application number: 13/496,537
- Filed: 2010-09-29
- Published: 2012-11-08
- Granted: 2017-09-05
- Earliest claimed: 2009-09-30
- Assignees: Sanofi-Aventis Deutschland GmbH
- Applicants: Garen Kouyoumjian; Robert Veasey; David Plumptre; Christopher Jones; Catherine Anne Macdonald; Matthew Jones
- Inventors: Garen Kouyoumjian; Robert Veasey; David Plumptre; Christopher Jones; Catherine Anne Macdonald; Matthew Jones
- Web page: https://patentgrep.com/patent/US9750890B2

## CPC

- A61M 5/31585: {the component being manually operated or triggered by an axially moving actuator operated by user, e.g. an axially movable injection button}
- A61M 5/24: Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
- A61M 5/31555: {by purely axial movement of dose setting member, e.g. during setting or filling of a syringe}
- A61M 5/3158: {the component being manually operated or triggered by an axially moving actuator operated by user, e.g. an axially movable injection button}
- A61M 5/3146: {Priming, e.g. purging, reducing backlash or clearance}
- A61M 2005/2407: {from the rear}
- A61M 2205/6081: Colour codes
- A61M 2207/00: Methods of manufacture, assembly or production
- Y10T 29/49826: Assembling or joining
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

## Abstract

The present invention relates to an assembly forming a piston rod for advancing a cartridge bung in a drug delivery device, the assembly comprising a first member and a second member wherein in a first state, the first and the second member are moveable with respect to each other to adjust the length of the piston rod and wherein in a second state the first member is locked in position with respect to the second member in order to define a fixed length of the piston rod. Furthermore, it relates to a drug delivery device comprising the assembly and to a method for assembling such a drug delivery device.

## Claims

### Claim 1

An assembly forming a piston rod for advancing a cartridge bung in a drug delivery device, the piston rod comprising:
a first member; and
a second member, where the first member and second member are moveably connected to each other along a common longitudinal axis to define a first length that is equal to a sum of a length of the second member plus a length of the first member that extends beyond the distal end of the second member when the piston rod is in a first state,
wherein when the piston rod is in the first state the second member does not move axially and the first member is axially moveable along the longitudinal axis with respect to the second member so that the first length of the piston rod can be increased to a fixed length and
wherein when the piston rod is in a second state the extension of the first member beyond the distal end of the second member is greater than in the first state and the first member is locked in axial position with respect to the second member in order to define the fixed length of the piston rod, where the locked position forms a rigid connection through threaded engagement between the first member and the second member such that the fixed length of the piston rod does not change when a dose of a fluid medicinal product is set and then dispensed.

### Claim 2 (depends on 1)

An assembly according to claim 1, wherein in the first state the first member is coupled to an adjustment member such that relative axial movement between the first member and the adjustment member is permitted and rotational movement relative to each other is prevented.

### Claim 3 (depends on 1)

An assembly according to claim 1, wherein the assembly comprises a threaded engagement between the first member and the second member.

### Claim 4 (depends on 3)

An assembly according to claim 3, wherein the threaded engagement is self-locking.

### Claim 5 (depends on 1)

An assembly according to claim 1, wherein the first member is at least partly arranged inside the second member.

### Claim 6 (depends on 2)

An assembly according to claim 2, wherein the adjustment member is arranged such that a rotational movement of the adjustment member relative to the second member advances the first member relative to the second member.

### Claim 7 (depends on 6)

An assembly according to claim 6, wherein the first member comprises a pad configured to abut an assembled cartridge bung while being advanced relative to the second member.

### Claim 8 (depends on 7)

An assembly according to claim 7, wherein the assembly comprises a means to detect the abutment of the pad upon the bung and to stop the movement of the first member.

### Claim 9 (depends on 1)

An assembly according to claim 1, wherein in the second state of the assembly the first member and the second member are suitable for moving the cartridge bung into an assembled cartridge for dispensing a fluid medicinal product.

### Claim 10 (depends on 2)

An assembly according to claim 2, wherein the adjustment member is located at a proximal end of the assembly.

### Claim 11 (depends on 2)

An assembly according to claim 2, wherein in the second state of the assembly the adjustment member is locked with the second member in order to prevent rotational and axial movement with respect to the second member.

### Claim 12 (depends on 2)

An assembly according to claim 2, wherein in the second state of the assembly the adjustment member is connected to the first member such that relative rotation and axial displacement between the adjustment member and the first member is prevented.

### Claim 13

An assembly forming a piston rod for advancing a cartridge bung in a drug delivery device, the piston rod comprising:
an adjustment member comprising an aperture;
a first member operatively engaged with the adjustment member such that the first member extends through the aperture and can move axially relative to the adjustment member when the piston rod is in a first state; and
a second member, where the first member and second member are axially and moveably connected to each other along a common longitudinal axis and through the adjustment member to define a first length when the piston rod is in the first state,
wherein when the piston rod is in the first state the second member does not move axially and the first member is axially moveable with respect to the second member as a result of movement of the adjustment member so that the first length of the piston rod can be increased to a fixed length, and
wherein when the piston rod is in a second state,
the first member is locked in position with respect to the second member in order to define the fixed length of the piston rod, where the locked position forms a rigid connection through threaded engagement between the first member and the second member such that the fixed length of the piston rod does not change when a dose of a fluid medicinal product is set and then dispensed; and
the adjustment member is locked with the second member in order to prevent rotational and axial movement with respect to the second member.
