# US 9,750,683 B2 · Antifungal compositions for the treatment of skin and nails

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- Number: US 9,750,683 B2
- Document ID: US9750683B2
- Status: Granted
- Kind: B2
- Application number: 14/378,937
- Filed: 2012-11-15
- Published: 2015-11-26
- Granted: 2017-09-05
- Earliest claimed: 2012-02-17
- Assignees: Veloce BioPharma, LLC
- Applicants: Joseph Capriotti; Kara Capriotti; Stuart Lessin
- Inventors: Joseph Capriotti; Kara Capriotti; Stuart Lessin
- Web page: https://patentgrep.com/patent/US9750683B2

## CPC

- A61K 9/0012: {Galenical forms characterised by the site of application}
- A61K 9/0014: {Skin, i.e. galenical aspects of topical compositions (non-active ingredients are additionally classified in A61K47/00; A61K9/0009, A61K9/0021, A61K9/7015, A61K9/7023 take precedence; cosmetic preparations A61K8/00, A61Q; preparations for wound dressings or bandages A61L26/00)}
- A61K 31/79: Polymers of vinyl pyrrolidone
- A61K 33/18: Iodine; Compounds thereof
- A61K 45/06: Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A61K 47/20: containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
- A61P 17/00: Drugs for dermatological disorders
- A61P 31/00: Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P 31/04: Antibacterial agents
- A61P 31/10: Antimycotics
- A61K 9/08: Solutions {(composition of solutions A61K47/00)}
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS

## Abstract

Disclosed herein are antifungal compositions for treatment of skin and nails, as well as methods of making and using the same.

## Claims

### Claim 1

A method for treating a skin disease complicated by microbial colonization or infection, said method comprising:
(a) providing a pharmaceutically acceptable composition comprising
0.1% to 10% (w/w) of a therapeutic agent which is povidone-iodine (PVP-I) wherein the 0.1% to 10% PVP-I is dissolved in
greater than 33% (w/w) DMSO and at least one co-solvent;
and a pharmaceutically acceptable carrier which is a gel to form a gel composition; and
(b) topically administering the composition to a patient in need of treatment of the skin disease, wherein the skin disease is molluscum contagiosum.