# US 9,750,555 B2 · Method and apparatus for cryoadhesion > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,750,555 B2 - Document ID: US9750555B2 - Status: Granted - Kind: B2 - Application number: 14/696,873 - Filed: 2015-04-27 - Published: 2015-08-13 - Granted: 2017-09-05 - Earliest claimed: 2013-03-14 - Assignees: Medtronic CryoCath LP - Applicants: Medtronic CryoCath LP - Inventors: Dan Wittenberger; Rachid Mahrouche - Web page: https://patentgrep.com/patent/US9750555B2 ## CPC - A61B 18/02: by cooling, e.g. cryogenic techniques - A61B 18/1492: {having a flexible, catheter-like structure, e.g. for heart ablation (A61B18/1477 takes precedence)} - A61B 2018/00041: {Heating, e.g. defrosting} - A61B 2018/0022: {Balloons} - A61B 2018/00351: {Heart} - A61B 2018/00577: {Ablation} - A61B 2018/00994: {combining two or more different kinds of non-mechanical energy or combining one or more non-mechanical energies with ultrasound} - A61B 2018/0212: {using an instrument inserted into a body lumen, e.g. catheter} - A61B 2018/0262: {using a circulating cryogenic fluid} - A61F 2007/0054: {with a closed fluid circuit, e.g. hot water} - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) ## Abstract A method and system for continuously delivering cryotreatment to a treatment device. In one embodiment, the system may include a first PID circuit in the fluid delivery line and a second PID circuit in the fluid return line, and the first and second PID circuits may operate simultaneously to continuously provide coolant to a cryotreatment device during the inflation phase, ablation phase, and warming (or thawing) phase while providing for temperature adjustment. Alternatively, the system may include a bypass line by which coolant may bypass the subcooler system and be delivered to the cryotreatment device at non-ablation temperatures during the inflation phase. During the ablation phase, coolant may flow through the subcooler system. ## Claims ### Claim 1 A continuous flow cryotreatment system, the cryotreatment system comprising: a fluid supply; a fluid injection line in communication with the fluid supply, the fluid injection line including a first PID circuit having a first PID controller, a first pressure transducer, and a first proportional valve; a cryotreatment device having a treatment element in communication with the fluid injection line; a fluid return line in communication with the cryotreatment device, the fluid return line including a second PID circuit having a second PID controller, a second pressure transducer, and a second proportional valve; a vacuum source in communication with the fluid return line; and the system being programmed to operate in an inflation phase, a treatment phase, and a warming phase, the first PID circuit and second PID circuit simultaneously operating to control the temperature of the treatment element during the inflation phase, the ablation phase, and the warming phase, the system being further programmed such that simultaneous operation of the first PID circuit and the second PID circuit being configured to continuously deliver a cryotreatment fluid to the cryotreatment device during all of the inflation phase, ablation phase, and warming phase. ### Claim 2 (depends on 1) The system of claim 1, wherein the treatment element defines an expansion chamber, the expansion chamber being in communication with the fluid injection line and the fluid return line, the treatment element having an adjustable temperature based at least in part on the flow of fluid within the expansion chamber from the fluid supply reservoir. ### Claim 3 (depends on 2) The system of claim 2, wherein the system further comprises a control unit in communication with the first PID circuit and the second PID circuit, first pressure transducer and the second pressure transducer each measuring pressure within the system, the control unit adjusting the first proportional valve and the second proportional valve based at least in part on the pressure measurements of the first proportional valve and the second proportional valve. ### Claim 4 (depends on 3) The system of claim 3, wherein the first pressure transducer measures pressure within the expansion chamber of the cryotreatment device. ### Claim 5 (depends on 3) The system of claim 3, wherein the temperature of the treatment element is decreased when the first proportional valve is adjusted to increase the flow rate of coolant into the expansion chamber and when the second proportional valve is adjusted to at least partially open the expansion chamber to the vacuum source. ### Claim 6 (depends on 5) The system of claim 5, wherein the temperature of the treatment element is increased when the first proportional valve is adjusted to reduce the flow rate of coolant into the expansion chamber and when the second proportional valve is adjusted to at least partially close the expansion chamber to the vacuum source. ### Claim 7 (depends on 6) The system of claim 6, wherein the treatment element is an inflatable element, the inflatable element remaining inflated throughout the treatment phase and warming phase. ### Claim 8 (depends on 7) The system of claim 7, wherein the treatment element is positioned proximate an area of target tissue during the treatment phase and the warming phase. ### Claim 9 (depends on 8) The system of claim 8, wherein the temperature of the treatment element during the warming phase is less than approximately 0° C. but greater than a temperature at which the treatment element ablates the target tissue. ### Claim 10 (depends on 9) The system of claim 9, wherein the first PID circuit and the second PID circuit each further include a solenoid valve. ### Claim 11 (depends on 1) The system of claim 1, wherein the first PID circuit controls a fluid injection pressure within the fluid injection line. ### Claim 12 (depends on 1) The system of claim 1, wherein the second PID circuit controls a fluid injection pressure within the fluid return line.