# US 9,750,524 B2 · Shape-set textile structure based mechanical thrombectomy systems > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,750,524 B2 - Document ID: US9750524B2 - Status: Granted - Kind: B2 - Application number: 14/926,636 - Filed: 2015-10-29 - Published: 2016-02-18 - Granted: 2017-09-05 - Earliest claimed: 2013-03-15 - Assignees: Insera Therapeutics, Inc. - Applicants: Insera Therapeutics, Inc. - Inventors: Vallabh Janardhan; Vikram Janardhan - Web page: https://patentgrep.com/patent/US9750524B2 ## CPC - A61B 17/320725: {with radially expandable cutting or abrading elements (A61B17/32075 takes precedence)} - A61B 17/22031: {Gripping instruments, e.g. forceps, for removing or smashing calculi (A61B17/221 takes precedence)} - A61B 17/22032: {having inflatable gripping elements (balloon catheters A61M25/10)} - A61B 17/221: Gripping devices in the form of loops or baskets {for gripping calculi or similar types of obstructions (surgical snare instruments A61B17/32056)} - A61B 17/3207: Atherectomy devices {working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions (A61B17/32037 takes precedence; endoscopic cutting instruments A61B17/320016)} - D04C 1/06: Braid or lace serving particular purposes - D04C 3/48: Auxiliary devices - A61B 2017/00778: {Operations on blood vessels (A61B2017/22097, A61B2017/320741 take precedence)} - A61B 2017/22001: {Angioplasty, e.g. PCTA} - A61B 2017/22034: {for gripping the obstruction or the tissue part from inside} - A61B 2017/2217: {single wire changing shape to a gripping configuration} - A61B 2090/3966: {Radiopaque markers visible in an X-ray image} - D10B 2401/046: Shape recovering or form memory - D10B 2509/06: Vascular grafts; stents - A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D) - D04C: BRAIDING OR MANUFACTURE OF LACE, INCLUDING BOBBIN-NET OR CARBONISED LACE; BRAIDING MACHINES; BRAID; LACE (machines for making soles from strips of material A43D29/00; cane working B27J1/00) - D10B: INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES ## Abstract A biomedical shape-set textile structure based mechanical thrombectomy systems and methods are described. In one of the embodiments, the mechanical thrombectomy device can be customized to the length of the clot in each patient. In one of the embodiments, the mechanical thrombectomy device because of the textile structure has a very low overall profile or thickness that is less than 0.0125 inches (0.317 mm) and therefore can be deployed within microcatheters with inner lumen diameter as small as 0.014 inches (0.355 mm). ## Claims ### Claim 1 A thrombectomy device comprising: a plurality of wires woven to form a textile structure having a collapsed configuration and an expanded configuration, the textile structure comprising five to ten self-expanding bulbs in the expanded configuration, at least three of the five to ten self-expanding bulbs having different outer diameters in the expanded configuration, a proximal end bulb of the five to ten self-expanding bulbs larger than at least one middle bulb of the five to ten self-expanding bulbs in the expanded configuration, wherein the plurality of wires comprises shape memory wires and radiopaque wires, and wherein the radiopaque wires are circumferentially clustered to enhance visibility under x-ray; and a delivery system proximal to the textile structure. ### Claim 2 (depends on 1) The device of claim 1, wherein at least one of the self-expanding bulbs has a spherical shape in the expanded configuration. ### Claim 3 (depends on 1) The device of claim 1, wherein the textile structure comprises five said self-expanding bulbs. ### Claim 4 (depends on 1) The device of claim 1, wherein the textile structure comprises six said self-expanding bulbs. ### Claim 5 (depends on 1) The device of claim 1, wherein the textile structure comprises ten said self-expanding bulbs. ### Claim 6 (depends on 1) The device of claim 1, wherein the delivery system comprises a multi-filament hybrid. ### Claim 7 (depends on 1) The device of claim 1, wherein the delivery system comprises a hypotube. ### Claim 8 (depends on 1) The device of claim 1, wherein the delivery system comprises a multi-filament hybrid, wherein the textile structure comprises six said self-expanding bulbs, wherein at least one of the self-expanding bulbs has a spherical shape in the expanded configuration. ### Claim 9 (depends on 1) The device of claim 1, wherein the delivery system comprises a multi-filament hybrid, wherein the textile structure comprises six said self-expanding bulbs, wherein each of the self-expanding bulbs has a spherical shape in the expanded configuration, and wherein the delivery system is coupled to the textile structure using solder comprising radiopaque material. ### Claim 10 A thrombectomy device comprising: a plurality of wires woven to form a textile structure having a collapsed configuration and an expanded configuration, the textile structure comprising: five to ten self-expanding bulbs in the expanded configuration, the five to ten self-expanding bulbs in the expanded configuration comprising three or more sizes in series and a proximal end bulb of the five to ten self-expanding bulbs larger than at least one middle bulb of the five to ten self-expanding bulbs in the expanded configuration, and a distal neck distal to and radially inward of a distal-most bulb of the self-expanding bulbs; and a delivery system having a distal end overlay bonded to the distal neck. ### Claim 11 (depends on 10) The device of claim 10, wherein the textile structure comprises six said self-expanding bulbs. ### Claim 12 (depends on 10) The device of claim 10, wherein the textile structure comprises ten said self-expanding bulbs. ### Claim 13 (depends on 10) The device of claim 10, wherein the delivery system comprises a multi-filament hybrid. ### Claim 14 (depends on 10) The device of claim 10, wherein the delivery system comprises a multi-filament hybrid, wherein the textile structure comprises six said self-expanding bulbs, wherein at least one of the self-expanding bulbs has a spherical shape in the expanded configuration, and wherein the plurality of wires comprises shape memory wires and radiopaque wires. ### Claim 15 A thrombectomy device comprising: a plurality of wires woven to form a textile structure having a collapsed configuration and an expanded configuration, the textile structure comprising five to ten self-expanding bulbs in the expanded configuration, the five to ten self-expanding bulbs in the expanded configuration comprising three or more sizes in series and a proximal end bulb of the five to ten self-expanding bulbs larger than at least one middle bulb of the five to ten self-expanding bulbs in the expanded configuration; a delivery system proximal to the textile structure; and a bonding zone where the delivery system is coupled to the textile structure, the bonding zone comprising solder, the solder comprising radiopaque material. ### Claim 16 (depends on 15) The device of claim 15, wherein the textile structure comprises six said self-expanding bulbs. ### Claim 17 (depends on 15) The device of claim 15, wherein the textile structure comprises ten said self-expanding bulbs. ### Claim 18 (depends on 15) The device of claim 15, wherein the delivery system comprises a multi-filament hybrid. ### Claim 19 (depends on 15) The device of claim 15, wherein the delivery system comprises a multi-filament hybrid, wherein the textile structure comprises six said self-expanding bulbs, wherein at least one of the self-expanding bulbs has a spherical shape in the expanded configuration, and wherein the plurality of wires comprises shape memory wires and radiopaque wires.