# US 9,750,247 B2 · Nematotoxic composition of synergistic effect, use of a nematotoxic composition of synergistic effect > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 9,750,247 B2 - Document ID: US9750247B2 - Status: Granted - Kind: B2 - Application number: 14/654,017 - Filed: 2013-12-26 - Published: 2015-11-05 - Granted: 2017-09-05 - Earliest claimed: 2012-12-26 - Assignees: Empresa Brasileira De Pesquisa AgropecuáRia—Embrapa; Unitversity of Melbourne - Applicants: Empresa Brasileira De Pesquisa Agropecuaria—Embrapa; The University of Melbourne - Inventors: Thales Lima Rocha; Raphael Garcia de Sousa Evaristo; Maria Fátima Grossi de Sá; Djair dos Santos de Lima e Souza; Maria Cristina Mattar da Silva; Vera Lúcia Perussi Polez; Ute Roessner; Tony Bacic - Web page: https://patentgrep.com/patent/US9750247B2 ## CPC - A01N 41/12: not containing sulfur-to-oxygen bonds, e.g. polysulfides - A01N 37/02: Saturated carboxylic acids or thio analogues thereof; Derivatives thereof - A01N 37/06: Unsaturated carboxylic acids or thio analogues thereof; Derivatives thereof - A01N 43/16: with oxygen as the ring hetero atom - A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS ## Abstract The present invention relates generically to compositions used for controlling agricultural pests and, in a particular embodiment, to compositions usable for combating nematodes. The invention presents a feasible alternative to the use of nematotoxic compounds that are harmful to the environment and that may damage human health. This alternative is embodied through a nematotoxic composition for controlling nematodes and that may be used on plants, parts of plants and on the soil. The respective technology results from unexpected results achieved from experiments carried out with extracts of the plant Canavalia ensiformis, resulting in an unheard-of nematotoxic composition comprising a specific combination of substances that are naturally found in the extract and that act synergistically. ## Claims ### Claim 1 A nematotoxic composition comprising, as active compounds: Palmitic acid; Trans-aconitic acid and/or glucose and, optionally, S-carboxymethylcisteine, wherein a combination of the palmitic acid, Trans-aconitic acid and/or glucose, and optionally S-carboxymethylcisteine exhibits synergy. ### Claim 2 (depends on 1) The nematotoxic composition according to claim 1, further comprising one or more formulation ingredients. ### Claim 3 (depends on 1) The nematotoxic composition according to claim 1, wherein the nematoxic composition is in a form selected from the group consisting of a solution, an emulsion, a wettable powder, a suspension, a power, a dust, a paste, a soluble powder, granules, a suspension-emulsion concentrate, a natural and/or synthetic material impregnated with the active compounds, and a microencapsulation in a polymeric substance. ### Claim 4 (depends on 2) The nematotoxic composition according to claim 2, wherein the formulation ingredients are one or more liquid carriers/liquid solvents and/or one or more solid carriers and/or one or more surfactants and/or one or more stickiness agents and/or one or more dyes. ### Claim 5 (depends on 4) The nematotoxic composition according to claim 4, wherein the formulation ingredients are one or more liquid carriers/liquid solvents and the liquid carriers/liquid solvents are selected from the group consisting of aromatic solvents, chlorinated aromatic solvents or chlorinated aliphatic hydrocarbons, aliphatic hydrocarbons, petroleum fractions, mineral oils, vegetable oils, alcohols and their ethers and esters, ketones, strongly polar solvents and water. ### Claim 6 (depends on 5) The nematotoxic composition according to claim 5, wherein the liquid carriers/liquid solvents are aromatic solvents selected from xylene, toluene or alkylnaphthalenes. ### Claim 7 (depends on 5) The nematotoxic composition according to claim 5, wherein the liquid carriers/liquid solvents are chlorinated aromatic solvents or chlorinated aliphatic hydrocarbons selected from chlorobensene, chloroethylene or dichloromethane. ### Claim 8 (depends on 5) The nematotoxic composition according to claim 5, wherein the liquid carriers/liquid solvents are aliphatic hydrocarbons selected from cyclohexane or paraffins. ### Claim 9 (depends on 5) The nematotoxic composition according to claim 5, wherein the liquid carriers/liquid solvents are alcohols selected from ethanol, propanol, butanol or glycol. ### Claim 10 (depends on 5) The nematotoxic composition according to claim 5, wherein the liquid carriers/liquid solvent are ketones selected from propanone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone. ### Claim 11 (depends on 5) The nematotoxic composition according to claim 5, wherein the liquid carriers/liquid solvents are strongly polar solvents selected from dimethylformamide or dimethyl sulfoxide. ### Claim 12 (depends on 4) The nematotoxic composition according to claim 4, wherein the solid carriers are selected from ammonium salts, ground natural minerals or ground synthetic minerals. ### Claim 13 (depends on 12) The nematotoxic composition according to claim 12, wherein the solid carriers are ground natural minerals selected from kaolin, clays, talc, chalk, quartz, atapulgite, montmorilonite or diatomaceous earth. ### Claim 14 (depends on 12) The nematotoxic composition according to claim 12, wherein the solid carriers are ground synthetic minerals selected from silica, alumina or silicates. ### Claim 15 (depends on 4) The nematotoxic composition according to claim 4, wherein the solid carriers are in the form of granules selected from ground natural rocks, synthetic granules or organic material granules. ### Claim 16 (depends on 4) The nematotoxic composition according to claim 4, wherein the formulation ingredients are one or more surfactants selected from emulsifiers and/or dispersants and/or foam builders. ### Claim 17 (depends on 16) The nematotoxic composition according to claim 16, wherein the formulation ingredients are the one or more emulsifiers selected from cationic, non-ionic or anionic emulsifiers. ### Claim 18 (depends on 17) The nematotoxic composition according to claim 17, wherein the one Of more emulsifiers are non-ionic and/or anionic emulsifiers selected from polyoxyethyele fatty esters, polyoxyethylene fatty ethers, alkyl sulfonates, alkyl sulfates, aryl sulfonates, and protein hydrolysates. ### Claim 19 (depends on 16) The nematotoxic composition according to claim 16, wherein the formulation ingredients are one or more dispersants selected from methylcellulose or lignin sulfite waste. ### Claim 20 (depends on 4) The nematotoxic composition according to claim 4, wherein the formulation ingredients are one or more stickiness agents selected from carboxymethylcellulose, natural polymers or synthetic polymers. ### Claim 21 (depends on 4) The nematotoxic composition according to claim 4, wherein the formulation ingredients are one or more dyes selected from inorganic pigments or organic dyes. ### Claim 22 (depends on 1) The nematotoxic composition according to claim 1, further comprising one or more additional active compounds. ### Claim 23 (depends on 22) The nematotoxic composition according to claim 22, wherein the one or more additional active compounds are selected from insecticides, attractors, sterilizing agents, bactericides, acaricides, namaticides, fungicides, growth-regulating substances, herbicides or safeners. ### Claim 24 (depends on 1) The nematotoxic composition according to claim 1, wherein the composition is an aqueous composition. ### Claim 25 (depends on 24) The nematotoxic composition according to claim 24, wherein the aqueous composition contains palmitic acid and trans-aconitic acid in a concentration of 0.25 g/L each. ### Claim 26 (depends on 24) The nematotoxic composition according to claim 24, wherein the aqueous composition contains palmitic acid and glucose in a concentration of 0.17 g/L each. ### Claim 27 (depends on 24) The nematotoxic composition according to claim 24, wherein the aqueous composition contains palmitic acid, trans-aconitic acid and glucose in a concentration of 0.17 g/L each. ### Claim 28 (depends on 24) The nematotoxic composition according to claim 24, wherein the aqueous composition contains palmitic acid, trans-aconitic acid and S-carboxymethylcisteine in a concentration of 0.17 g/L each. ### Claim 29 (depends on 24) The nematotoxic composition according to claim 24, wherein the aqueous composition contains palmitic acid, glucose and S-carboxymethylcisteine in a concentration of 0.17 g/L each. ### Claim 30 (depends on 24) The nematotoxic composition according to claim 24, wherein the aqueous composition contains palmitic acid, trans-aconitic acid, glucose and S-carboxymethylcisteine in a concentration of 0.25 g/L each. ### Claim 31 (depends on 1) A method for controlling nematodes on a plant, comprising: applying the nematotoxic composition according to claim 1 to the plant and/or to parts of the plant and/or to the soil to control nematodes on the plant. ### Claim 32 (depends on 31) The method according to claim 31, wherein the nematoxic composition is applied to the plant. ### Claim 33 (depends on 31) The method according to claim 31, wherein the nematodes are Meloidogyne incognita.